iPTMnet Report for Q06190 (PPP2R3A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q06190 / P2R3A_HUMAN
Protein Name Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
Gene Name Name: PPP2R3A
Synonyms:PPP2R3;
Organism Homo sapiens (Human)

PRO ID PR:Q06190
DAG View
PRO Name serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha (human)
Definition A serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha that is encoded in the genome of human.
Short Label hPPP2R3A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q06190 (PPP2R3A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S61 Phosphorylation Q13535 (ATR) neXtProt 10608806
S101 Phosphorylation PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
S181 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
K238 Acetylation PhosphoSitePlus
K245 Acetylation PhosphoSitePlus
T270 Phosphorylation PhosphoSitePlus
Y334 Phosphorylation PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
T501 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus
K535 Methylation PhosphoSitePlus
S537 Phosphorylation phospho.ELM 18669648
S562 Phosphorylation PhosphoSitePlus
T573 Phosphorylation PhosphoSitePlus
T683 Phosphorylation PhosphoSitePlus
S684 Phosphorylation PhosphoSitePlus
S692 Phosphorylation PhosphoSitePlus
S862 Phosphorylation PhosphoSitePlus
T868 Phosphorylation PhosphoSitePlus
S933 Phosphorylation PhosphoSitePlus
T945 Phosphorylation PhosphoSitePlus
T949 Phosphorylation PhosphoSitePlus
K1074 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K35 Acetylation PhosphoSitePlus
K38 Acetylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
T247 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S61 Y61 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S155 L155 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S181 L181 Biomuta DOID:4159 / skin cancer [ cosmic ]
S188 F188 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S188 Y188 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T270 S270 Biomuta DOID:1324 / lung cancer [ cosmic ]
S341 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S345 Y345 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S503 F503 Biomuta DOID:4159 / skin cancer [ cosmic ]
S505 R505 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
T573 K573 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S684 F684 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T949 R949 Biomuta DOID:9256 / colorectal cancer [ cosmic ]