iPTMnet Report for Q06136 (KDSR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q06136 / KDSR_HUMAN
Protein Name 3-ketodihydrosphingosine reductase precursor
Gene Name Name: KDSR
Synonyms:FVT1,SDR35C1;
Organism Homo sapiens (Human)

PRO ID PR:Q06136
DAG View
PRO Name 3-ketodihydrosphingosine reductase (human)
Definition A 3-ketodihydrosphingosine reductase that is encoded in the genome of human.
Short Label hKDSR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q06136 (KDSR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T60 Phosphorylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
T137 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
Y207 Phosphorylation PhosphoSitePlus
Y210 Phosphorylation PhosphoSitePlus
Y215 Phosphorylation PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S136 T136 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T137 S137 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S172 P172 Biomuta DOID:10534 / stomach cancer [ cosmic ]