iPTMnet Report for Q06033 (ITIH3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q06033 / ITIH3_HUMAN
Protein Name Inter-alpha-trypsin inhibitor heavy chain H3 precursor
Gene Name Name: ITIH3
Organism Homo sapiens (Human)

PRO ID PR:Q06033
DAG View
PRO Name inter-alpha-trypsin inhibitor heavy chain H3 (human)
Definition An inter-alpha-trypsin inhibitor heavy chain H3 that is encoded in the genome of human.
Short Label hITIH3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q06033 (ITIH3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N91 N-Glycosylation GlyGen   UniProt 16335952, 29741879
T124 Phosphorylation PhosphoSitePlus
Y167 Phosphorylation PhosphoSitePlus
Y170 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
T360 Phosphorylation PhosphoSitePlus
R368 Methylation PhosphoSitePlus
S386 Phosphorylation PhosphoSitePlus
T387 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
K571 Acetylation PhosphoSitePlus
N580 N-Glycosylation GlyGen   UniProt 16335952, 23090970
Y592 Phosphorylation PhosphoSitePlus
S700 Phosphorylation PhosphoSitePlus
S703 Phosphorylation PhosphoSitePlus
K832 Methylation PhosphoSitePlus
K840 Methylation PhosphoSitePlus
T847 O-Glycosylation GlyGen 36240223
Site PTM Type PTM Enzyme Score Source PMID
T705 Phosphorylation HPRD 20068231
T727 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y167 C167 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S700 N700 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]