iPTMnet Report for Q05940 (SLC18A2)
Protein Information
UniProt AC / UniProt ID | Q05940 / VMAT2_HUMAN |
Protein Name | Synaptic vesicular amine transporter |
Gene Name | Name: SLC18A2 Synonyms:SVMT,VMAT2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q05940 |
PRO Name | synaptic vesicular amine transporter (human) |
Definition | A synaptic vesicular amine transporter that is encoded in the genome of human. |
Short Label | hSLC18A2 |
Category | organism-gene |
Q05940 (SLC18A2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S15 | Phosphorylation | score2 | PhosphoSitePlus | 24321511 | ||
S15 | Phosphorylation | P17252 (PRKCA) | score2 | PhosphoSitePlus | 24321511 | |
S18 | Phosphorylation | score2 | PhosphoSitePlus | 24321511 | ||
S18 | Phosphorylation | P17252 (PRKCA) | score2 | PhosphoSitePlus | 24321511 | |
S240 | Phosphorylation | score1 | PhosphoSitePlus | |||
S279 | Phosphorylation | score1 | PhosphoSitePlus | |||
T283 | Phosphorylation | score1 | PhosphoSitePlus | |||
T286 | Phosphorylation | score1 | PhosphoSitePlus | |||
T287 | Phosphorylation | score1 | PhosphoSitePlus | |||
S511 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus | 18088087, 9045708 | ||
S513 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus | 18088087, 9045708 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S511 | Phosphorylation | score2 | HPRD | 18088087, 9045708 | ||
S511 | Phosphorylation | P19784 (CSNK2A2) | score2 | HPRD | 18088087, 9045708 | |
S511 | Phosphorylation | P48729 (CSNK1A1) | score2 | HPRD | 18088087, 9045708 | |
S511 | Phosphorylation | P68400 (CSNK2A1) | score2 | HPRD | 18088087, 9045708 | |
S513 | Phosphorylation | score0 | HPRD | 18088087 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T287 | M287 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S511 | Y511 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S513 | N513 | Biomuta | DOID:1319 / brain cancer [ cosmic ] |