iPTMnet Report for Q05932 (FPGS)
Protein Information
| UniProt AC / UniProt ID | Q05932 / FOLC_HUMAN |
| Protein Name | Folylpolyglutamate synthase, mitochondrial precursor |
| Gene Name | Name: FPGS |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q05932 |
| PRO Name | folylpolyglutamate synthase, mitochondrial (human) |
| Definition | A folylpolyglutamate synthase, mitochondrial that is encoded in the genome of human. |
| Short Label | hFPGS |
| Category | organism-gene |
DAG ViewQ05932 (FPGS) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| M43 | Acetylation | score1 | UniProt | 22814378 | ||
| Y61 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K66 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K154 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K238 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K243 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K248 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C315 | Methylation | score1 | IEDB | 31844290 | ||
| K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S403 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C439 | Methylation | score1 | IEDB | 31844290 | ||
| S539 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K107 | E107 | Biomuta | DOID:263 / kidney cancer [ cosmic ] |
