iPTMnet Report for Q05655 (PRKCD)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q05655 / KPCD_HUMAN
Protein Name Protein kinase C delta type
Gene Name Name: PRKCD
Synonyms:PKCD;
Organism Homo sapiens (Human)

PRO ID PR:Q05655
DAG View
PRO Name protein kinase C delta type (human)
Definition A protein kinase C delta type that is encoded in the genome of human.
Short Label hPRKCD
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q05655 (PRKCD) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T43 Phosphorylation PhosphoSitePlus
T50 Phosphorylation PhosphoSitePlus   UniProt 17965192
Y52 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 11927579, 15302935
Y64 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 21865164, 11927579, 15302935, ...18434324, 11739733, 24569990
T85 Phosphorylation IEDB 32387766
K113 Sumoylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus   UniProt 18669648
S133 Phosphorylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
T141 Phosphorylation Q05655 (PRKCD) PhosphoSitePlus   RLIMS-P   Signor   UniProt 17965192, 19366211, 23186163
Y155 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21865164, 11927579, 25472878, ...28237688, 15302935, 24569990, 15774464
C175 Methylation IEDB 31844290
K184 Ubiquitination PhosphoSitePlus
Y187 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 15302935, 18434324, 11739733, ...8824297
T218 Phosphorylation Q05655 (PRKCD) PhosphoSitePlus   Signor   UniProt 19369195, 19366211
K222 Ubiquitination PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
T295 Phosphorylation Q05655 (PRKCD) PhosphoSitePlus   RLIMS-P   Signor 19366211, 25755284
S299 Phosphorylation Q05655 (PRKCD) IntAct   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17603046, 29860841, 23186163, ...18691976
S302 Phosphorylation Q05655 (PRKCD) IntAct   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17603046, 23186163, 19366211, ...18669648, 10329716
S304 Phosphorylation Q05655 (PRKCD) IntAct   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17603046, 17965192, 23186163, ...19366211, 21406692, 18669648, 18088087, 20068231
S306 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
Y313 Phosphorylation P07948 (LYN) , P00519 (ABL1) , P08631 (HCK) , P00533 (EGFR) , P07947 (YES1) , P06241 (FYN) , P12931 (SRC) , P09619 (PDGFRB) , P06239 (LCK) neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 10713049, 18387943, ...17126298, 19369195, 11381116, 20190138, 15302935, 19366211, 18083107, 17569658, 17570831, 19690332, 25755284, 17956904
K319 Ubiquitination PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
T333 Phosphorylation PhosphoSitePlus
Y334 Phosphorylation P07947 (YES1) , P00533 (EGFR) , P06241 (FYN) , P09619 (PDGFRB) , P12931 (SRC) , P07948 (LYN) IntAct   neXtProt   phospho.ELM   PhosphoSitePlus 18387943, 17956904, 20190138, ...19366211, 12024011, 18083107, 17569658
K336 Ubiquitination PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
S359 Phosphorylation IEDB   PhosphoSitePlus 32387766
K362 Ubiquitination PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
Y374 Phosphorylation PhosphoSitePlus   UniProt 20068231
C415 Methylation IEDB 31844290
Y448 Phosphorylation PhosphoSitePlus
T451 Phosphorylation PhosphoSitePlus   UniProt 17965192
Y453 Phosphorylation PhosphoSitePlus
Y471 Phosphorylation PhosphoSitePlus
K475 Sumoylation PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
S503 Phosphorylation Q05655 (PRKCD) PhosphoSitePlus   Signor   UniProt 18691976, 19366211, 23186163
S506 Phosphorylation PhosphoSitePlus   UniProt 17965192
T507 Phosphorylation O15530 (PDPK1) , Q05655 (PRKCD) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17965192, 19366211, 9748166, ...16505477, 15302935, 11781095, 19801500
T511 Phosphorylation PhosphoSitePlus
Y514 Phosphorylation PhosphoSitePlus
Y525 Phosphorylation PhosphoSitePlus
Y567 Phosphorylation PhosphoSitePlus   UniProt 17570831
K581 Ubiquitination PhosphoSitePlus
T594 Phosphorylation PhosphoSitePlus
T605 Phosphorylation PhosphoSitePlus
T609 Phosphorylation PhosphoSitePlus
K613 Ubiquitination PhosphoSitePlus
Y630 Phosphorylation PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus
K641 Ubiquitination PhosphoSitePlus
S645 Phosphorylation Q05655 (PRKCD) IEDB   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15731106, 21406692, 19366211, ...15302935, 27158772, 28237688, 19801500, 16489124, 32387766, 20068231, 9305920
Y646 Phosphorylation PhosphoSitePlus
S647 Phosphorylation PhosphoSitePlus
S654 Phosphorylation PhosphoSitePlus   UniProt 18691976
S658 Phosphorylation PhosphoSitePlus   UniProt 18691976
S664 Phosphorylation phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   UniProt 18691976, 17965192, 31585731, ...23186163, 19369195, 15302935, 18669648, 24275569, 19690332, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S37 Phosphorylation HPRD 18691976
T43 Phosphorylation HPRD 18691976
T50 Phosphorylation HPRD 18691976
Y52 Phosphorylation P07948 (LYN) HPRD 7575560, 10945993
Y64 Phosphorylation P07948 (LYN) HPRD 7575560, 10945993
Y120 Phosphorylation HPRD 18691976
S130 Phosphorylation HPRD 18691976, 18669648
Y155 Phosphorylation P07948 (LYN) HPRD 7575560, 10945993
Y187 Phosphorylation P07948 (LYN) HPRD 7575560, 10945993
T295 Phosphorylation HPRD 18691976
S299 Phosphorylation HPRD 18691976, 18669648, 20068231
S302 Phosphorylation HPRD 18691976, 18669648, 20068231, ...18452278
S304 Phosphorylation HPRD 18691976, 18669648, 18088087, ...20068231, 18452278
S306 Phosphorylation HPRD 18669648
S307 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231
Y313 Phosphorylation P06239 (LCK) HPRD 17016520, 18691976, 17389395, ...11381116, 18083107, 16497976
S331 Phosphorylation HPRD 19413330, 18691976
T333 Phosphorylation HPRD 18691976
Y334 Phosphorylation P06239 (LCK) HPRD 18083107, 18691976, 11381116
Y374 Phosphorylation HPRD 18083107, 20068231
S503 Phosphorylation HPRD 18691976
S506 Phosphorylation HPRD 18691976, 18669648, 20058876
T507 Phosphorylation O15530 (PDPK1) HPRD 11381116, 18669648, 20058876, ...19664995, 9748166
T511 Phosphorylation HPRD 18669648, 20058876
Y514 Phosphorylation P06239 (LCK) HPRD 11381116
Y567 Phosphorylation P07948 (LYN) HPRD 7575560, 10945993
S645 Phosphorylation Q05655 (PRKCD) HPRD 18691976, 19651622, 17322306, ...18669648, 20166139, 20068231
Y646 Phosphorylation HPRD 18669648
S647 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231
S654 Phosphorylation HPRD 18691976, 18669648
S658 Phosphorylation HPRD 18691976, 18669648, 20058876
S664 Phosphorylation Q05513 (PRKCZ) HPRD 18691976, 20058876, 15302935, ...11381116, 18452278, 18669648, 20068231


Q05655 (PRKCD) as PTM Enzyme



Substrate Site Score Source PMID
O00429-4 (DNM1L) S579 neXtProt 21119009
O00429 (DNM1L) S616 PhosphoSitePlus   Signor 21119009, 17301055
O14939 (PLD2) T566 neXtProt   PhosphoSitePlus   Signor 20733000
O15162 (PLSCR1) T161 HPRD   neXtProt   Signor 10770950
O15350 (TP73) S289 neXtProt   PhosphoSitePlus   Signor 12097319
O76090 (BEST1) S358 PhosphoSitePlus   Signor 19635817
O95817 (BAG3) S187 PhosphoSitePlus   Signor 23108398
P00533-1 (EGFR) T678 HPRD 2987962, 2984676
P04040 (CAT) S167 PhosphoSitePlus 24211614
P04406 (GAPDH) T246 PhosphoSitePlus 23653351
P04637 (TP53) S15 neXtProt 16314418
P04637 (TP53) S46 PhosphoSitePlus   Signor 16377624
P04792 (HSPB1) S15 neXtProt 15731106
P04792 (HSPB1) S86 neXtProt 15731106
P05107 (ITGB2) S745 PhosphoSitePlus   Signor 11700305
P05107 (ITGB2) T758 PhosphoSitePlus   Signor 18550856, 11700305
P05198 (EIF2S1) S52 HPRD 9819435, 10542257, 1677563
P05787 (KRT8) S74 PhosphoSitePlus   Signor 15972820
P07108 (DBI) T42 Signor 18194441
P07550 (ADRB2) S261 HPRD 1848190
P07550 (ADRB2) S262 HPRD 1848190
P07550 (ADRB2) S345 HPRD 1848190
P07550 (ADRB2) S346 HPRD 1848190
P08581 (MET) S985 PhosphoSitePlus 15075332
P08913 (ADRA2A) S247 HPRD 11732925
P10588 (NR2F6) S83 PhosphoSitePlus   Signor 18701084
P10636-2 (MAPT) S204 HPRD 8999860, 9771888, 10090741, ...12387894, 9832145, 7706316, 9735171
P10636-8 (MAPT) S262 HPRD 8999860, 9771888, 10090741, ...12387894, 9832145, 7706316, 9735171
P10636-2 (MAPT) S267 HPRD 9771888, 10737616, 12387894, ...9832145, 7706316, 12435421
P10636-6 (MAPT) S298 HPRD 9771888, 10737616, 12387894, ...9832145, 7706316, 12435421
P10636-8 (MAPT) S356 HPRD 9771888, 10737616, 12387894, ...9832145, 7706316, 12435421
P11413 (G6PD) S180 Signor 20649491
P11413-3 (G6PD) S210 PhosphoSitePlus 20649491
P11413 (G6PD) T236 Signor 20649491
P11413-3 (G6PD) T266 PhosphoSitePlus 20649491
P11831 (SRF) T160 neXtProt 15282327
P12830 (CDH1) T790 RLIMS-P+ 27203386
P12931 (SRC) S12 PhosphoSitePlus   Signor 18069897
P13498 (CYBA) T147 PhosphoSitePlus 19948736
P13796 (LCP1) S5 PhosphoSitePlus 20169155, 19799649
P14598 (NCF1) S303 neXtProt   PhosphoSitePlus   Signor 12056906
P14598 (NCF1) S304 neXtProt   PhosphoSitePlus   Signor 12056906
P14598 (NCF1) S315 neXtProt   PhosphoSitePlus   Signor 12056906
P14598 (NCF1) S320 neXtProt   PhosphoSitePlus   Signor 12056906
P14598 (NCF1) S328 neXtProt   PhosphoSitePlus   Signor 12056906
P14598 (NCF1) S359 neXtProt   PhosphoSitePlus   Signor 12056906
P14598 (NCF1) S370 neXtProt   PhosphoSitePlus   Signor 12056906
P14598 (NCF1) S379 neXtProt   PhosphoSitePlus   Signor 12056906
P15941-7 (MUC1) T224 HPRD 11877440
P15941-11 (MUC1) T233 HPRD 11877440
P15941-8 (MUC1) T242 HPRD 11877440
P15941 (MUC1) T1224 PhosphoSitePlus   Signor 11877440
P17096 (HMGA1) S44 Signor 10617144
P17096 (HMGA1) S64 Signor 10617144
P17302 (GJA1) S368 neXtProt 20338032
P17405 (SMPD1) S510 Signor 17303575
P18433-6 (PTPRA) S180 HPRD 19651622, 11923305, 11676480
P18433 (PTPRA) S189 HPRD   Signor 19651622, 11923305, 11676480
P18433 (PTPRA) S204 HPRD   neXtProt 12826681, 11923305, 11676480
P18433-5 (PTPRA) S213 HPRD   Signor 11923305, 11676480
P19086 (GNAZ) S16 HPRD 8429024, 9166747, 7559455
P19086 (GNAZ) S27 HPRD   Signor 8429024, 9166747, 7559455
P19429 (TNNI3) S23 neXtProt   PhosphoSitePlus   Signor 18550549, 19366211
P19429 (TNNI3) S24 neXtProt   PhosphoSitePlus   Signor 18550549, 19366211
P19429 (TNNI3) T143 neXtProt   PhosphoSitePlus   Signor 24585778, 18550549, 19366211
P21730 (C5AR1) S334 PhosphoSitePlus   Signor 17145764, 10636859, 12464600
P23396 (RPS3) S6 neXtProt   PhosphoSitePlus   Signor 19059439, 15950189
P23396 (RPS3) T221 neXtProt   PhosphoSitePlus   Signor 19059439
P25098 (GRK2) S29 HPRD   Signor 11042191
P26010-1 (ITGB7) T783 HPRD 12682249
P28329-3 (CHAT) S440 HPRD   PhosphoSitePlus 15381704
P28329-3 (CHAT) S476 HPRD   PhosphoSitePlus 15381704
P28329 (CHAT) S558 HPRD   Signor 15381704
P28329-1 (CHAT) S594 HPRD   Signor 15381704
P29353 (SHC1) S28 Signor 16963224
P29353-2 (SHC1) S29 PhosphoSitePlus 16963224
P29353 (SHC1) S139 neXtProt   Signor 16963224
P29474 (NOS3) T495 Signor 24379783
P30086 (PEBP1) S153 HPRD   PhosphoSitePlus   Signor 14654844, 20166139, 12551925, ...20068231
P30411 (BDKRB2) S373 HPRD   Signor 11517230
P31431-1 (SDC4) S179 HPRD 9556568, 11916978
P31946 (YWHAB) S60 neXtProt   Signor 9705322, 16024783
P35222 (CTNNB1) S715 PhosphoSitePlus   Signor 25639486
P35568 (IRS1) S307 PhosphoSitePlus 15516986, 14583092
P35568 (IRS1) S323 PhosphoSitePlus   Signor 16611834, 15516986, 14583092, ...15069075
P35568 (IRS1) S362 neXtProt 18285345, 14583092
P35568 (IRS1) S441 PhosphoSitePlus 16611834
P35568 (IRS1) S574 PhosphoSitePlus 15516986, 14583092
P35568 (IRS1) S616 Signor 15143153
P35568 (IRS1) S1101 HPRD 15364919
P35611-1 (ADD1) S695 HPRD 8810272, 9679146
P35611-3 (ADD1) S726 HPRD   PhosphoSitePlus 17341583, 8810272, 9679146
P35612-1 (ADD2) S713 HPRD 18452278, 8810272, 19664994, ...9679146
P35612-1 (ADD2) S726 HPRD 8810272, 9679146
P38936 (CDKN1A) S146 neXtProt 17431791
P40189 (IL6ST) T890 HPRD   neXtProt   PhosphoSitePlus   Signor 12361954
P40189-1 (IL6ST) T909 HPRD   neXtProt 12361954
P40763-2 (STAT3) S726 HPRD 19413330, 18691976, 12763138, ...9343414, 12576423, 20058876, 11350938, 9872331, 10521505, 18669648, 18491316, 14551213, 20068231
P40763 (STAT3) S727 HPRD   PhosphoSitePlus   Signor 19413330, 18691976, 12763138, ...10446219, 12576423, 16951338, 20058876, 11350938, 9872331, 10521505, 18669648, 18491316, 14551213, 16418226, 20068231, 9343414
P41143 (OPRD1) S344 HPRD   Signor 11085981
P41594-2 (GRM5) S840 HPRD 15894802
P42224-1 (STAT1) S727 HPRD   neXtProt   PhosphoSitePlus   Signor 18691976, 15322115, 20058876, ...17502367, 7543024, 12817007, 18452278, 11839738, 11972023, 18669648, 14963018, 7690989, 9355737, 12637327, 20068231
P45983 (MAPK8) S129 neXtProt 16483929
P48048-2 (KCNJ1) S164 HPRD 8621594
P48048-1 (KCNJ1) S183 HPRD 8621594
P49023-2 (PXN) T538 neXtProt 20388733
P49840 (GSK3A) S21 HPRD   PhosphoSitePlus   Signor 11884598, 19413330, 12054501, ...18691976, 11749387, 11035810
P49841 (GSK3B) S9 PhosphoSitePlus 11884598
P51398 (DAP3) S31 PhosphoSitePlus 18227431
P51398 (DAP3) S185 PhosphoSitePlus 18227431
P51398 (DAP3) T186 PhosphoSitePlus 18227431
P51398 (DAP3) T237 PhosphoSitePlus   Signor 18227431
P51398 (DAP3) S280 PhosphoSitePlus 18227431
P52757 (CHN2) S171 neXtProt   PhosphoSitePlus   Signor 20335173
P53004 (BLVRA) S21 PhosphoSitePlus 22584576
P53004 (BLVRA) S33 PhosphoSitePlus 22584576
P53004 (BLVRA) S230 PhosphoSitePlus 22584576
P53004 (BLVRA) S237 PhosphoSitePlus 22584576
P53671 (LIMK2) S283 neXtProt   PhosphoSitePlus   Signor 16820362, 15923181
P61073 (CXCR4) S324 PhosphoSitePlus   Signor 10521508, 20048153
P61073 (CXCR4) S325 PhosphoSitePlus   Signor 10521508, 20048153
P61073 (CXCR4) S338 Signor 10521508
P61073 (CXCR4) S339 Signor 10521508
P61978 (HNRNPK) S302 HPRD   PhosphoSitePlus   Signor 10329716
P62753 (RPS6) S235 PhosphoSitePlus 15471950
P62753 (RPS6) S236 PhosphoSitePlus 15471950
P63104 (YWHAZ) S58 HPRD   neXtProt   Signor 12861023, 9705322
P68104 (EEF1A1) T432 HPRD 7890750, 20068231
P68431 (H3C12) T46 Signor 19363025
P78536 (ADAM17) T735 PhosphoSitePlus 18722532
P98082 (DAB2) S24 HPRD   PhosphoSitePlus   Signor 10542228, 15280374
Q01543 (FLI1) T312 PhosphoSitePlus   Signor 25707716, 19158279, 21321929, ...24058639
Q01995 (TAGLN) S181 HPRD 20166139, 11053353, 18212344
Q02297-6 (NRG1) S286 PhosphoSitePlus 23720309
Q04917 (YWHAH) S59 neXtProt 9705322
Q05655 (PRKCD) T141 PhosphoSitePlus   Signor 19366211
Q05655 (PRKCD) T218 PhosphoSitePlus   Signor 19366211
Q05655 (PRKCD) T295 PhosphoSitePlus   Signor 19366211, 25755284
Q05655 (PRKCD) S299 PhosphoSitePlus   Signor   UniProt 17603046
Q05655 (PRKCD) S302 PhosphoSitePlus   Signor   UniProt 17603046, 19366211
Q05655 (PRKCD) S304 PhosphoSitePlus   Signor   UniProt 17603046, 19366211
Q05655 (PRKCD) S503 PhosphoSitePlus   Signor 19366211
Q05655 (PRKCD) T507 Signor   UniProt 17965192, 19366211
Q05655 (PRKCD) S645 HPRD   neXtProt   PhosphoSitePlus   Signor 15731106, 17322306, 18691976, ...19366211, 19651622, 18669648, 20166139, 16489124, 20068231, 9305920
Q09472 (EP300) S89 HPRD   neXtProt   PhosphoSitePlus   Signor 11020388, 12379484
Q13263 (TRIM28) S473 Signor 18590578
Q13887 (KLF5) S153 HPRD   Signor 12682370
Q14247 (CTTN) S405 PhosphoSitePlus 26490115
Q14896 (MYBPC3) S275 Signor 17075052
Q14896 (MYBPC3) S284 Signor 17075052
Q14896 (MYBPC3) S304 Signor 17075052
Q15078 (CDK5R1) S59 neXtProt 19965374
Q15078 (CDK5R1) S65 neXtProt 19965374
Q15078 (CDK5R1) S124 neXtProt 19965374
Q15080-3 (NCF4) T154 HPRD   Signor 9804763
Q15139 (PRKD1) S412 PhosphoSitePlus 21726532
Q15139 (PRKD1) S738 neXtProt   PhosphoSitePlus   Signor 15024053
Q15139 (PRKD1) S742 neXtProt   PhosphoSitePlus   Signor 15024053
Q15438-2 (CYTH1) S393 HPRD 11438522
Q15438-1 (CYTH1) S394 HPRD   Signor 11438522
Q15438-2 (CYTH1) T394 HPRD 11438522
Q15438-1 (CYTH1) T395 HPRD   Signor 11438522
Q15717 (ELAVL1) S221 neXtProt   PhosphoSitePlus   Signor 18285462, 20086103
Q15717 (ELAVL1) S318 neXtProt   PhosphoSitePlus   Signor 18285462, 20086103, 21310943
Q15797 (SMAD1) S463 neXtProt 20927330
Q15797 (SMAD1) S465 neXtProt 20927330
Q16206 (ENOX2) S504 PhosphoSitePlus   Signor 22659163
Q16236-1 (NFE2L2) S40 HPRD 12198130
Q16658 (FSCN1) S39 HPRD   Signor 19651622, 8999969, 8647875, ...20068231
Q16820 (MEP1B) S687 HPRD 12941954
Q5JVS0-1 (HABP4) T354 HPRD   Signor 14699138
Q5JVS0-1 (HABP4) T375 HPRD   Signor 14699138
Q8IV61 (RASGRP3) T133 PhosphoSitePlus 15657177
Q92793-1 (CREBBP) S437 HPRD 11463380
Q96A00 (PPP1R14A) T38 PhosphoSitePlus 12144526
Q96C90 (PPP1R14B) T57 PhosphoSitePlus 12144526
Q96D96 (HVCN1) T29 PhosphoSitePlus 20037153
Q96D96 (HVCN1) S97 PhosphoSitePlus 20037153
Q99808 (SLC29A1) S281 PhosphoSitePlus   Signor 25725289
Q99986 (VRK1) T355 neXtProt 21346188
Q9BZK7 (TBL1XR1) S123 PhosphoSitePlus   Signor 18374649
Q9H257 (CARD9) T231 neXtProt   PhosphoSitePlus 22265677
Q9HBA0 (TRPV4) S162 PhosphoSitePlus 19661060
Q9HBA0 (TRPV4) T175 PhosphoSitePlus 19661060
Q9HBA0 (TRPV4) S189 PhosphoSitePlus 19661060
Q9NPP4 (NLRC4) S533 neXtProt 22885697
Q9NQ66-1 (PLCB1) S887 HPRD 11278470
Q9NRY6 (PLSCR3) T21 PhosphoSitePlus   Signor 16267027
Q9UBS0 (RPS6KB2) S473 PhosphoSitePlus   Signor 12529391
Q9UQ80 (PA2G4) S360 PhosphoSitePlus   Signor 21145366, 16642037, 17316401
Q9UQL6 (HDAC5) S259 PhosphoSitePlus   Signor 21146494, 18332134
Q9UQL6 (HDAC5) S498 Signor 18332134
Q9Y243-1 (AKT3) S472 HPRD 12162751
Q9Y2R2 (PTPN22) S35 PhosphoSitePlus   Signor 18056643


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048916 (hPRKCD/Phos:2) pT507 PRO
PR:000048917 (hPRKCD/Phos:3) pT507,pS645,pS664 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q05655 (PRKCD) T507 P15941 (MUC1) increased_association eFIP 28692035


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S37 N37 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T43 P43 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
Y52 H52 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T141 M141 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S299 T299 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S299 F299 Biomuta [ cosmic ]
S302 L302 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S306 Y306 Biomuta DOID:1324 / lung cancer [ cosmic ]
S307 L307 Biomuta DOID:1324 / lung cancer [ cosmic ]
S341 N341 Biomuta DOID:363 / uterine cancer [ cosmic ]
K362 * Biomuta DOID:263 / kidney cancer [ cosmic ]
Y374 S374 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y471 C471 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T511 N511 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y525 N525 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T609 S609 Biomuta DOID:1612 / breast cancer [ cosmic ]
K641 E641 Biomuta DOID:1612 / breast cancer [ cosmic ]
S645 F645 Biomuta DOID:4159 / skin cancer [ cosmic ]