iPTMnet Report for Q05519 (SRSF11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q05519 / SRS11_HUMAN
Protein Name Serine/arginine-rich splicing factor 11
Gene Name Name: SRSF11
Synonyms:SFRS11;
Organism Homo sapiens (Human)

PRO ID PR:Q05519
DAG View
PRO Name serine/arginine-rich splicing factor 11 (human)
Definition A serine/arginine-rich splicing factor 11 that is encoded in the genome of human.
Short Label hSRSF11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q05519 (SRSF11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 22814378
T5 Phosphorylation PhosphoSitePlus
T32 Phosphorylation PhosphoSitePlus
T51 Phosphorylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
C79 S-Nitrosylation dbSNO 19483679
K82 Ubiquitination PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
S207 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18847512, 18669648, 24275569, 19690332, 20068231
S209 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus 18669648, 18847512
K211 Ubiquitination PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus   UniProt 23186163
K217 Ubiquitination PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
T260 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S262 Phosphorylation PhosphoSitePlus
S263 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 33465208, 34019948, 32119511, 35289036, 28510447, 34229054
S263 Phosphorylation PhosphoSitePlus
S264 O-Glycosylation GlyGen 33465208
S264 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S287 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S289 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S295 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S297 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 33465208, 34019948, 32119511, 35289036, 28510447, 34229054
S297 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S306 Phosphorylation PhosphoSitePlus
T307 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus   UniProt 23186163
T325 Phosphorylation PhosphoSitePlus   UniProt 23186163
K328 Acetylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
T332 Phosphorylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
T352 Phosphorylation PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus
S360 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S366 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S368 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S370 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 33465208, 34019948, 32119511, 35289036, 28510447, 34229054
S370 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S394 Phosphorylation PhosphoSitePlus
T395 Phosphorylation PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus   UniProt 20068231
Y425 Phosphorylation PhosphoSitePlus
Y432 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S434 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 24275569, 20068231
T447 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231
S449 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 20068231, 21406692, 17081983, ...24275569
T452 Phosphorylation PhosphoSitePlus
S456 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K459 Acetylation PhosphoSitePlus
T461 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus   UniProt 20068231
S468 Phosphorylation PhosphoSitePlus
S483 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 19690332, 20068231
Site PTM Type PTM Enzyme Score Source PMID
T32 Phosphorylation HPRD 18491316
S207 Phosphorylation HPRD 17322306, 18212344, 18767875, ...19664995, 18452278, 19651622, 18669648, 20166139, 19415658, 20068231, 17924679
S209 Phosphorylation HPRD 18669648, 20068231
S212 Phosphorylation HPRD 20068231
S215 Phosphorylation HPRD 20068231
T260 Phosphorylation HPRD 17081983, 20068231
S262 Phosphorylation HPRD 20068231
S264 Phosphorylation HPRD 17081983, 20068231
S277 Phosphorylation HPRD 20068231
S279 Phosphorylation HPRD 20068231
S295 Phosphorylation HPRD 17081983, 20068231
S297 Phosphorylation HPRD 17081983, 20068231
S323 Phosphorylation HPRD 20068231
T325 Phosphorylation HPRD 20068231
S336 Phosphorylation HPRD 19651622, 20068231
S338 Phosphorylation HPRD 19651622, 20068231
S340 Phosphorylation HPRD 19651622, 20068231
S348 Phosphorylation HPRD 19651622
S350 Phosphorylation HPRD 19651622
T352 Phosphorylation HPRD 19651622
S354 Phosphorylation HPRD 19651622
S360 Phosphorylation HPRD 19651622, 20068231
S366 Phosphorylation HPRD 17081983, 20068231, 17924679
S368 Phosphorylation HPRD 17081983, 20068231, 17924679
S370 Phosphorylation HPRD 17081983, 20068231
S412 Phosphorylation HPRD 20068231
S414 Phosphorylation HPRD 20068231
Y432 Phosphorylation HPRD 18669648
S434 Phosphorylation HPRD 19413330, 17081983, 19691289, ...18452278, 19651622, 18669648, 20166139, 20068231
T447 Phosphorylation HPRD 17081983, 20068231, 19664995
S449 Phosphorylation HPRD 17081983, 18212344, 19664995, ...18452278, 19651622, 18707149, 20166139, 20068231, 17924679
S456 Phosphorylation HPRD 18669648
S464 Phosphorylation HPRD 20068231
S483 Phosphorylation HPRD 17322306, 18452278, 19651622, ...18669648, 18707149, 19415658, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S433 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S70 L70 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
S212 L212 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ]
S215 C215 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S215 Y215 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S231 T231 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S279 F279 Biomuta DOID:4159 / skin cancer [ cosmic ]
S295 F295 Biomuta DOID:4159 / skin cancer [ cosmic ]
S297 F297 Biomuta DOID:4159 / skin cancer [ cosmic ]
K328 R328 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K328 E328 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S336 C336 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S449 F449 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ]
K459 N459 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ]