Protein Information

Cytoscape View

UniProt AC / UniProt ID Q05516 / ZBT16_HUMAN
Protein Name Zinc finger and BTB domain-containing protein 16
Gene Name Name: ZBTB16
Organism Homo sapiens (Human)

PRO ID PR:Q05516
DAG View
PRO Name zinc finger and BTB domain-containing protein 16 (human)
Definition A zinc finger and BTB domain-containing protein 16 that is encoded in the genome of human.
Short Label hZBTB16
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q05516 (ZBTB16) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K154 Ubiquitination PhosphoSitePlus
S184 Phosphorylation RLIMS-P 25821988
S197 Phosphorylation P24941 (CDK2) neXtProt   PhosphoSitePlus   Signor 18246121
K242 Sumoylation PhosphoSitePlus
T282 Phosphorylation P24941 (CDK2) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 18246121, 25821988
Y334 Phosphorylation PhosphoSitePlus
K387 Methylation PhosphoSitePlus
K387 Sumoylation PhosphoSitePlus
K396 Methylation PhosphoSitePlus
K396 Sumoylation PhosphoSitePlus
T569 Phosphorylation PhosphoSitePlus
T597 Phosphorylation PhosphoSitePlus
Y630 Phosphorylation PhosphoSitePlus
K647 Acetylation PhosphoSitePlus
K650 Acetylation PhosphoSitePlus
K653 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T401 Phosphorylation HPRD 18452278
S407 Phosphorylation HPRD 18452278

Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:P29590-5 (hPML/iso:5) Interaction PR:Q05516 (hZBTB16) PRO 9294197

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S184 N184 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
Y334 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
K387 N387 Biomuta DOID:3571 / liver cancer [ icgc ]
T597 P597 Biomuta DOID:10534 / stomach cancer [ icgc, tcga ]
K650 E650 Biomuta DOID:363 / uterine cancer [ tcga ]