iPTMnet Report for Q05195 (MXD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q05195 / MAD1_HUMAN
Protein Name Max dimerization protein 1
Gene Name Name: MXD1
Synonyms:MAD;
Organism Homo sapiens (Human)

PRO ID PR:Q05195
DAG View
PRO Name max dimerization protein 1 (human)
Definition A max dimerization protein 1 that is encoded in the genome of human.
Short Label hMXD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q05195 (MXD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K39 Acetylation PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
T93 Phosphorylation PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
S145 Phosphorylation P23443 (RPS6KB1) , Q9UBS0 (RPS6KB2) , P31749 (AKT1) , Q15418 (RPS6KA1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 18451027, 19526459
R189 Methylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus
Y201 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S197 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S90 I90 Biomuta DOID:3571 / liver cancer [ cosmic ]
T94 M94 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
R189 W189 Biomuta [ cosmic ]
S191 R191 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]