iPTMnet Report for Q04756 (HGFAC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q04756 / HGFA_HUMAN
Protein Name Hepatocyte growth factor activator precursor
Gene Name Name: HGFAC
Organism Homo sapiens (Human)

PRO ID PR:Q04756
DAG View
PRO Name hepatocyte growth factor activator (human)
Definition A hepatocyte growth factor activator that is encoded in the genome of human.
Short Label hHGFAC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q04756 (HGFAC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T70 O-Glycosylation GlyGen 30459171
S92 O-Glycosylation GlyGen 30459171
S94 O-Glycosylation GlyGen 30459171
S95 O-Glycosylation GlyGen 30459171
R113 Methylation PhosphoSitePlus
R130 Methylation PhosphoSitePlus
N290 N-Glycosylation GlyGen 23090970, 29391424
T382 O-Glycosylation GlyGen 30459171
N468 N-Glycosylation GlyGen   UniProt 16335952, 18077410, 19159218, ...23090970, 29741879, 29671580
N492 N-Glycosylation GlyGen 29391424
N546 N-Glycosylation GlyGen 29391424
Site PTM Type PTM Enzyme Score Source PMID
N468 N-Glycosylation PRO 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S92 L92 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R113 S113 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R130 G130 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
N468 S468 Biomuta DOID:10534 / stomach cancer [ cosmic ]
N468 H468 Biomuta DOID:9256 / colorectal cancer [ cosmic ]