Protein Information

Cytoscape View


UniProt AC / UniProt ID Q04750 / TOP1_MOUSE
Protein Name DNA topoisomerase 1
Gene Name Name: Top1
Synonyms:Top-1;
Organism Mus musculus (Mouse)

PRO ID PR:Q04750
DAG View
PRO Name DNA topoisomerase 1 (mouse)
Definition A type 1B DNA topoisomerase 1 that is encoded in the genome of mouse.
Short Label mTOP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q04750 (Top1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S10 Phosphorylation PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
S114 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
K174 Acetylation PhosphoSitePlus   UniProt 23806337
K254 Ubiquitination PhosphoSitePlus
Y270 Phosphorylation phospho.ELM   PhosphoSitePlus 15448168
T271 Phosphorylation PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
C506 S-Nitrosylation dbSNO 20925432
C632 S-Nitrosylation dbSNO 20925432
K714 Acetylation PhosphoSitePlus
Y725 Phosphorylation PhosphoSitePlus