Protein Information

Cytoscape View


UniProt AC / UniProt ID Q04695 / K1C17_HUMAN
Protein Name Keratin, type I cytoskeletal 17
Gene Name Name: KRT17
Organism Homo sapiens (Human)

PRO ID PR:Q04695
DAG View
PRO Name keratin, type I cytoskeletal 17 (human)
Definition A keratin, type I cytoskeletal 17 that is encoded in the genome of human.
Short Label hKRT17
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q04695 (KRT17) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO
T2 Phosphorylation PhosphoSitePlus
T9 O-Glycosylation GlyGen 23301498, 22121020, 26853435, ...30059200, 22967762
S10 O-Glycosylation GlyGen 23301498, 22121020, 26853435, ...30059200, 22967762
S10 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17322306, 18669648, 20068231
S11 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S12 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 18212344
S13 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 18212344, 18767875, ...18669648, 20068231, 20068230
K15 Methylation PhosphoSitePlus
K15 Sumoylation PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
S17 Phosphorylation HPRD   PhosphoSitePlus 18212344
S18 Phosphorylation HPRD   PhosphoSitePlus 18212344
S24 Phosphorylation HPRD   PhosphoSitePlus 18212344
S25 Phosphorylation PhosphoSitePlus
T27 Phosphorylation HPRD   PhosphoSitePlus 20068231
S28 Phosphorylation HPRD   PhosphoSitePlus 18669648
S32 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 16964243, ...18767875, 19007248, 17322306, 18669648, 20068231, 18212344
S39 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 18212344, 19007248, ...18669648, 20068231, 17081983
S44 Phosphorylation PhosphoSitePlus   UniProt 22006917
Y69 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
Y98 Phosphorylation PhosphoSitePlus
K101 Acetylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
T110 Phosphorylation PhosphoSitePlus   UniProt 23186163
K115 Sumoylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
Y120 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
Y134 Phosphorylation PhosphoSitePlus
Y135 Phosphorylation PhosphoSitePlus
T171 Phosphorylation HPRD 20068231
K172 Acetylation PhosphoSitePlus
K172 Methylation PhosphoSitePlus
K172 Sumoylation PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
T175 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y217 Phosphorylation PhosphoSitePlus
K219 Sumoylation PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
Y260 Phosphorylation PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
K278 Methylation PhosphoSitePlus
K278 Sumoylation PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
T288 Phosphorylation PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y367 Phosphorylation PhosphoSitePlus
K368 Ubiquitination PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
T383 Phosphorylation PhosphoSitePlus
Y384 Phosphorylation PhosphoSitePlus
Y398 Phosphorylation PhosphoSitePlus
K399 Sumoylation PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
K400 Sumoylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
T410 Phosphorylation HPRD   PhosphoSitePlus 18212344
K419 Sumoylation PhosphoSitePlus
K419 Ubiquitination PhosphoSitePlus
T431 O-Glycosylation GlyGen 23301498, 22121020, 26853435, ...30059200, 22967762


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036269 (hKRT17/Ac:1) acM1 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S17 F17 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S24 L24 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S28 F28 Biomuta DOID:1909 / melanoma [ tcga ]
K115 T115 Biomuta DOID:5041 / esophageal cancer [ icgc ]
K278 N278 Biomuta DOID:3070 / malignant glioma [ tcga ]
S295 N295 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S323 F323 Biomuta DOID:1909 / melanoma [ icgc, tcga ]