Protein Information

Cytoscape View


UniProt AC / UniProt ID Q04089 / DOT1_YEAST
Protein Name Histone-lysine N-methyltransferase, H3 lysine-79 specific
Gene Name Name: DOT1
Synonyms:KMT4,PCH1;OrderedLocusNames:YDR440W;ORFNames:D9461.26;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

PRO ID PR:Q04089
DAG View
PRO Name histone-lysine N-methyltransferase, H3 lysine-79 specific (yeast)
Definition A protein that is a translation product of the DOT1 gene in yeast.
Short Label yDOT1
Category organism-gene

Interactive Sequence View

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Q04089 (DOT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation SGD 33334889, 35183557
S19 Phosphorylation SGD 33334889, 35183557
S24 Phosphorylation SGD 33334889, 35183557
S30 Phosphorylation RLIMS-P   SGD 33334889, 35183557
K43 Ubiquitination SGD 23749301
S49 Phosphorylation SGD 35183557
K50 Ubiquitination SGD 23749301
S74 Phosphorylation SGD 33334889, 35183557
T145 Phosphorylation SGD 33334889, 35183557
S174 Phosphorylation RLIMS-P   SGD 33334889, 35183557
S176 Phosphorylation RLIMS-P   SGD 33334889, 35183557
T208 Phosphorylation RLIMS-P   SGD 33334889, 35183557
S219 Phosphorylation BioGRID   SGD 33334889, 32597660, 33491328, ...18407956, 35183557
T223 Phosphorylation SGD 23749301
S227 Phosphorylation SGD 33334889, 35183557
K336 Acetylation SGD 22865919
S565 Phosphorylation SGD 33334889, 35183557
T576 Phosphorylation BioGRID   SGD 19684113, 35183557, 32597660, ...33334889
Y580 Phosphorylation BioGRID 19684113