Protein Information

Cytoscape View


UniProt AC / UniProt ID Q03963 / E2AK2_MOUSE
Protein Name Interferon-induced, double-stranded RNA-activated protein kinase
Gene Name Name: Eif2ak2
Synonyms:Pkr,Prkr,Tik;
Organism Mus musculus (Mouse)

PRO ID PR:Q03963
DAG View
PRO Name interferon-induced, double-stranded RNA-activated protein kinase (mouse)
Definition An interferon-induced, double-stranded RNA-activated protein kinase that is encoded in the genome of mouse.
Short Label mEIF2AK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q03963 (Eif2ak2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T31 Phosphorylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
K68 Acetylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
T409 Phosphorylation PhosphoSitePlus
T414 Phosphorylation PhosphoSitePlus


Q03963 (Eif2ak2) as PTM Enzyme



Substrate Site Score Source PMID
P35569 (Irs1) S307 PhosphoSitePlus 20144759
Q6ZWX6 (Eif2s1) S52 PhosphoSitePlus 20559319, 11832212


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P97868 (Rbbp6) S246 Q03963 (Eif2ak2) unknown eFIP 32175843