iPTMnet Report for Q03933 (HSF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q03933 / HSF2_HUMAN
Protein Name Heat shock factor protein 2
Gene Name Name: HSF2
Synonyms:HSTF2;
Organism Homo sapiens (Human)

PRO ID PR:Q03933
DAG View
PRO Name heat shock factor protein 2 (human)
Definition A heat shock factor protein 2 that is encoded in the genome of human.
Short Label hHSF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q03933 (HSF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K51 Ubiquitination PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K82 Sumoylation PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K135 Sumoylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K139 Sumoylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
K151 Sumoylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
C278 Methylation IEDB 31844290
K420 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S384 Phosphorylation PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K135 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K135 R135 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C278 F278 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K396 E396 Biomuta DOID:1324 / lung cancer [ cosmic ]
K420 N420 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]