Protein Information

Cytoscape View


UniProt AC / UniProt ID Q03154 / ACY1_HUMAN
Protein Name Aminoacylase-1
Gene Name Name: ACY1
Organism Homo sapiens (Human)

PRO ID PR:Q03154
DAG View
PRO Name aminoacylase-1 (human)
Definition An aminoacylase-1 that is encoded in the genome of human.
Short Label hACY1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q03154 (ACY1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K4 Ubiquitination PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
Y107 Phosphorylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
R386 Methylation PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K129 E129 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
K218 T218 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]