iPTMnet Report for Q03154 (ACY1)
Protein Information
| UniProt AC / UniProt ID | Q03154 / ACY1_HUMAN |
| Protein Name | Aminoacylase-1 |
| Gene Name | Name: ACY1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q03154 |
| PRO Name | aminoacylase-1 (human) |
| Definition | An aminoacylase-1 that is encoded in the genome of human. |
| Short Label | hACY1 |
| Category | organism-gene |
DAG ViewQ03154 (ACY1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K4 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K100 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y107 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K115 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K129 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K218 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K221 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K244 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K332 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R386 | Methylation | score1 | PhosphoSitePlus | |||
| S408 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K129 | E129 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K129 | R129 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K218 | T218 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K244 | T244 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K332 | N332 | Biomuta | DOID:3953 / adrenal gland cancer [ cosmic ] | |
| R386 | C386 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
