Protein Information

Cytoscape View


UniProt AC / UniProt ID Q03113 / GNA12_HUMAN
Protein Name Guanine nucleotide-binding protein subunit alpha-12
Gene Name Name: GNA12
Organism Homo sapiens (Human)

PRO ID PR:Q03113
DAG View
PRO Name guanine nucleotide-binding protein subunit alpha-12 (human)
Definition A guanine nucleotide-binding protein subunit alpha-12 that is encoded in the genome of human.
Short Label hGNA12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q03113 (GNA12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S40 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
Y121 Phosphorylation PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
R235 Methylation PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S68 I68 Biomuta DOID:363 / uterine cancer [ tcga ]
Y121 D121 Biomuta DOID:2394 / ovarian cancer [ tcga ]
R235 C235 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:3070 / malignant glioma [ tcga ]
R235 H235 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:2394 / ovarian cancer [ icgc, tcga ] DOID:2994 / germ cell cancer [ cosmic ]
K376 N376 Biomuta DOID:3963 / thyroid carcinoma [ cosmic ]