iPTMnet Report for Q03113 (GNA12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q03113 / GNA12_HUMAN
Protein Name Guanine nucleotide-binding protein subunit alpha-12
Gene Name Name: GNA12
Organism Homo sapiens (Human)

PRO ID PR:Q03113
DAG View
PRO Name guanine nucleotide-binding protein subunit alpha-12 (human)
Definition A guanine nucleotide-binding protein subunit alpha-12 that is encoded in the genome of human.
Short Label hGNA12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q03113 (GNA12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S40 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
Y121 Phosphorylation PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
R235 Methylation PhosphoSitePlus
T369 Phosphorylation IEDB 35494241
K376 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S68 G68 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K219 R219 Biomuta DOID:4159 / skin cancer [ cosmic ]
R235 H235 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2394 / ovarian cancer [ cosmic, icgc ]
R235 C235 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:1319 / brain cancer [ icgc ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
T369 N369 Biomuta DOID:4159 / skin cancer [ cosmic ]
K376 N376 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]