iPTMnet Report for Q02930 (CREB5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q02930 / CREB5_HUMAN
Protein Name Cyclic AMP-responsive element-binding protein 5
Gene Name Name: CREB5
Synonyms:CREBPA;
Organism Homo sapiens (Human)

PRO ID PR:Q02930
DAG View
PRO Name cyclic AMP-responsive element-binding protein 5 (human)
Definition A cyclic AMP-responsive element-binding protein 5 that is encoded in the genome of human.
Short Label hCREB5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q02930 (CREB5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y3 Phosphorylation PhosphoSitePlus
T59 Phosphorylation PhosphoSitePlus   UniProt 20068231
T61 Phosphorylation PhosphoSitePlus   UniProt 20068231
S100 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus   UniProt 20068231
R172 Methylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
T254 Phosphorylation PhosphoSitePlus
T353 Phosphorylation PhosphoSitePlus
T355 Phosphorylation PhosphoSitePlus
T362 Phosphorylation PhosphoSitePlus
K432 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T59 Phosphorylation HPRD 20068231
T61 Phosphorylation HPRD 20068231
S137 Phosphorylation HPRD 20068231
S142 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T52 Phosphorylation HPRD 20068231
T54 Phosphorylation HPRD 20068231
S130 Phosphorylation HPRD 20068231
S135 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T26 Phosphorylation HPRD 20068231
T28 Phosphorylation HPRD 20068231
S104 Phosphorylation HPRD 20068231
S109 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y3 D3 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T28 I28 Biomuta [ cosmic ]
T54 I54 Biomuta [ cosmic ]
T61 I61 Biomuta [ cosmic ]
S100 L100 Biomuta DOID:4159 / skin cancer [ cosmic ]
T254 A254 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]