iPTMnet Report for Q02846 (GUCY2D)
Protein Information
| UniProt AC / UniProt ID | Q02846 / GUC2D_HUMAN |
| Protein Name | Retinal guanylyl cyclase 1 precursor |
| Gene Name | Name: GUCY2D Synonyms:CORD6,GUC1A4,GUC2D; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q02846 |
| PRO Name | retinal guanylyl cyclase 1 (human) |
| Definition | A retinal guanylyl cyclase 1 that is encoded in the genome of human. |
| Short Label | hGUCY2D |
| Category | organism-gene |
DAG ViewQ02846 (GUCY2D) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C17 | Methylation | score1 | IEDB | 31844290 | ||
| S200 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S214 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y283 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S298 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C622 | Methylation | score1 | IEDB | 31844290 | ||
| S645 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19413330 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y283 | C283 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
| S298 | N298 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |
