iPTMnet Report for Q02809 (PLOD1)
Protein Information
UniProt AC / UniProt ID | Q02809 / PLOD1_HUMAN |
Protein Name | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 precursor |
Gene Name | Name: PLOD1 Synonyms:LLH,PLOD; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q02809 |
PRO Name | procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (human) |
Definition | A procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 that is encoded in the genome of human. |
Short Label | hPLOD1 |
Category | organism-gene |
Q02809 (PLOD1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y53 | Phosphorylation | score1 | PhosphoSitePlus | |||
K68 | Ubiquitination | score1 | PhosphoSitePlus | |||
S146 | Phosphorylation | score1 | PhosphoSitePlus | |||
S165 | O-Glycosylation | score1 | GlyGen | 33214551, 30397120, 34725712, ... | ||
N197 | N-Glycosylation | score1 | GlyGen | 29741879, 24190977 | ||
T199 | O-Glycosylation | score1 | GlyGen | 33214551, 30397120, 34725712, ... | ||
Y256 | Phosphorylation | score1 | IEDB | 35494241 | ||
Y344 | Phosphorylation | score1 | PhosphoSitePlus | |||
S392 | Phosphorylation | score1 | PhosphoSitePlus | |||
K401 | Ubiquitination | score1 | PhosphoSitePlus | |||
T409 | Phosphorylation | score1 | PhosphoSitePlus | |||
S431 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y434 | Phosphorylation | score1 | PhosphoSitePlus | |||
S525 | Phosphorylation | score1 | PhosphoSitePlus | |||
N538 | N-Glycosylation | score1 | GlyGen | 34089345, 29741879, 24190977 | ||
K541 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y619 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y675 | Phosphorylation | score1 | PhosphoSitePlus | |||
N686 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
T714 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
R715 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N197 | D197 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S392 | N392 | Biomuta | [ cosmic ] | |
N686 | Y686 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |