Protein Information

Cytoscape View

UniProt AC / UniProt ID Q02556 / IRF8_HUMAN
Protein Name Interferon regulatory factor 8
Gene Name Name: IRF8
Organism Homo sapiens (Human)

PRO ID PR:Q02556
DAG View
PRO Name interferon regulatory factor 8 (human)
Definition An interferon regulatory factor 8 that is encoded in the genome of human.
Short Label hIRF8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q02556 (IRF8) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
Y107 Phosphorylation PhosphoSitePlus
Y110 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
Y211 Phosphorylation RLIMS-P 27149934
K240 Ubiquitination PhosphoSitePlus
K269 Methylation PhosphoSitePlus
Y373 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K269 E269 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]