iPTMnet Report for Q02556 (IRF8)
Protein Information
| UniProt AC / UniProt ID | Q02556 / IRF8_HUMAN |
| Protein Name | Interferon regulatory factor 8 |
| Gene Name | Name: IRF8 Synonyms:ICSBP1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q02556 |
| PRO Name | interferon regulatory factor 8 (human) |
| Definition | An interferon regulatory factor 8 that is encoded in the genome of human. |
| Short Label | hIRF8 |
| Category | organism-gene |
DAG ViewQ02556 (IRF8) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y107 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y110 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S151 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S162 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S164 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y211 | Phosphorylation | score0 | RLIMS-P | 27149934 | ||
| K240 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K269 | Methylation | score1 | PhosphoSitePlus | |||
| Y373 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C410 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y107 | N107 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S164 | F164 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K269 | E269 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
