iPTMnet Report for Q02535 (ID3)
Protein Information
| UniProt AC / UniProt ID | Q02535 / ID3_HUMAN |
| Protein Name | DNA-binding protein inhibitor ID-3 |
| Gene Name | Name: ID3 Synonyms:1R21,BHLHB25,HEIR1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q02535 |
| PRO Name | DNA-binding protein inhibitor ID-3 (human) |
| Definition | A DNA-binding protein inhibitor ID-3 that is encoded in the genome of human. |
| Short Label | hID3 |
| Category | organism-gene |
Q02535 (ID3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K2 | Acetylation | score1 | PhosphoSitePlus | |||
| K2 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S5 | Phosphorylation | P24941 (CDK2) | score4 | HPRD IEDB phospho.ELM PhosphoSitePlus RLIMS-P Signor | 17322306, 9372912, 34171305, ... | |
| C10 | Methylation | score1 | IEDB | 31844290 | ||
| Y11 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 25090023 | ||
| S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C47 | Methylation | score1 | IEDB | 31844290 | ||
| Y48 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 25090023 | ||
| T62 | Phosphorylation | score0 | RLIMS-P | 29026069 | ||
| S65 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 29026069 |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000036429 (hID3/iso:1/Phos:1) | pS5 | PRO | 9372912 |
PTM-dependent PPI
| PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q02535 (ID3) | S5 | P19419 (ELK1) | unknown | eFIP | 25693514 | |
| Phosphorylation | Q02535 (ID3) | S65 | Q14676 (MDC1) | unknown | eFIP | 29026069 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C10 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K30 | T30 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| C47 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| Y48 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| Y48 | H48 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| Y48 | C48 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| Y48 | S48 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S65 | I65 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S65 | R65 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |
DAG View