iPTMnet Report for Q02487 (DSC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q02487 / DSC2_HUMAN
Protein Name Desmocollin-2 precursor
Gene Name Name: DSC2
Synonyms:CDHF2,DSC3;
Organism Homo sapiens (Human)

PRO ID PR:Q02487
DAG View
PRO Name desmocollin-2 (human)
Definition A desmocollin-2 that is encoded in the genome of human.
Short Label hDSC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q02487 (DSC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N34 N-Glycosylation GlyGen 23090970, 29741879, 29391424, ...32125861, 24190977
K134 Acetylation PhosphoSitePlus
T278 Phosphorylation PhosphoSitePlus
N392 N-Glycosylation GlyGen   UniProt 29741879, 19139490, 29671580, ...29391424, 16740002
T524 Phosphorylation PhosphoSitePlus
S526 Phosphorylation PhosphoSitePlus
N546 N-Glycosylation GlyGen   UniProt 16335952, 29741879, 29391424
S552 Phosphorylation PhosphoSitePlus
N629 N-Glycosylation GlyGen   UniProt 29741879, 16740002, 29391424
N675 N-Glycosylation GlyGen 29391424
Y751 Phosphorylation PhosphoSitePlus
T760 Phosphorylation PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus
T783 Phosphorylation PhosphoSitePlus
T805 Phosphorylation PhosphoSitePlus
S808 Phosphorylation PhosphoSitePlus
R810 Methylation PhosphoSitePlus
T814 Phosphorylation PhosphoSitePlus
Y821 Phosphorylation PhosphoSitePlus
T822 Phosphorylation PhosphoSitePlus
Y823 Phosphorylation PhosphoSitePlus
S824 Phosphorylation PhosphoSitePlus
S828 Phosphorylation PhosphoSitePlus
Y839 Phosphorylation PhosphoSitePlus
Y853 Phosphorylation PhosphoSitePlus
Y857 Phosphorylation PhosphoSitePlus
Y859 Phosphorylation PhosphoSitePlus
S864 Phosphorylation PhosphoSitePlus   UniProt 24275569
S868 Phosphorylation PhosphoSitePlus   UniProt 24275569
S873 Phosphorylation PhosphoSitePlus   UniProt 24275569
K890 Ubiquitination PhosphoSitePlus
K900 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N392 N-Glycosylation PRO 29741879, 29671580
Y823 Phosphorylation HPRD 17016520, 15951569
Site PTM Type PTM Enzyme Score Source PMID
Y823 Phosphorylation HPRD 17016520, 15951569
S838 Phosphorylation PhosphoSitePlus
T843 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N392 D392 Biomuta DOID:1324 / lung cancer [ cosmic ]
S526 L526 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y751 H751 Biomuta DOID:1319 / brain cancer [ cosmic ]
T814 M814 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S824 L824 Biomuta DOID:1324 / lung cancer [ cosmic ]
S828 C828 Biomuta [ cosmic ]
S838 F838 Biomuta DOID:4159 / skin cancer [ cosmic ]
T843 A843 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y857 C857 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S864 L864 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
S868 F868 Biomuta DOID:363 / uterine cancer [ icgc ]
S873 C873 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K890 T890 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K900 E900 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]