iPTMnet Report for Q02413 (DSG1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q02413 / DSG1_HUMAN
Protein Name Desmoglein-1 precursor
Gene Name Name: DSG1
Synonyms:CDHF4;
Organism Homo sapiens (Human)

PRO ID PR:Q02413
DAG View
PRO Name desmoglein-1 (human)
Definition A desmoglein-1 that is encoded in the genome of human.
Short Label hDSG1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q02413 (DSG1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus
Y32 Phosphorylation PhosphoSitePlus
T38 Phosphorylation PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
C77 S-Nitrosylation dbSNO 24105792
N110 N-Glycosylation GlyGen   UniProt 23090970, 16740002, 24190977
S206 Phosphorylation PhosphoSitePlus
T215 Phosphorylation PhosphoSitePlus
T220 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
K450 Acetylation PhosphoSitePlus
Y515 Phosphorylation PhosphoSitePlus
T519 Phosphorylation PhosphoSitePlus
T520 Phosphorylation PhosphoSitePlus
S579 Phosphorylation PhosphoSitePlus   UniProt 20068231
S630 Phosphorylation PhosphoSitePlus
Y633 Phosphorylation PhosphoSitePlus
T634 Phosphorylation PhosphoSitePlus
Y637 Phosphorylation PhosphoSitePlus
T652 Phosphorylation PhosphoSitePlus
Y672 Phosphorylation PhosphoSitePlus
Y1042 Phosphorylation PhosphoSitePlus
S1043 Phosphorylation PhosphoSitePlus
T1044 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T220 Phosphorylation HPRD 20068231
S437 Phosphorylation HPRD 20068231
S579 Phosphorylation HPRD 20068231
S1029 Phosphorylation HPRD 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S23 N23 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S43 L43 Biomuta DOID:4159 / skin cancer [ cosmic ]
S65 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S206 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T215 N215 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T220 M220 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S437 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T519 P519 Biomuta DOID:4159 / skin cancer [ cosmic ]
S630 L630 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
Y637 H637 Biomuta DOID:1324 / lung cancer [ cosmic ]