iPTMnet Report for Q02383 (SEMG2)
Protein Information
| UniProt AC / UniProt ID | Q02383 / SEMG2_HUMAN |
| Protein Name | Semenogelin-2 precursor |
| Gene Name | Name: SEMG2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q02383 |
| PRO Name | semenogelin-2 (human) |
| Definition | A semenogelin-2 that is encoded in the genome of human. |
| Short Label | hSEMG2 |
| Category | organism-gene |
Q02383 (SEMG2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N272 | N-Glycosylation | score4 | GlyGen UniProt | 8665956, 26791533 | ||
| S347 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y348 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S350 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S351 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S352 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T353 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K363 | Methylation | score1 | PhosphoSitePlus | |||
| S407 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y408 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S410 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S411 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S412 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T413 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K423 | Acetylation | score1 | PhosphoSitePlus | |||
| T485 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S519 | O-Glycosylation | score1 | GlyGen | 30237853 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S351 | L351 | Biomuta | DOID:2021 / placenta cancer [ cosmic ] | |
| T353 | R353 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K363 | T363 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S407 | P407 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S411 | L411 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| T413 | A413 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| K423 | N423 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| T485 | M485 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View