iPTMnet Report for Q02318 (CYP27A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q02318 / CP27A_HUMAN
Protein Name Sterol 26-hydroxylase, mitochondrial precursor
Gene Name Name: CYP27A1
Synonyms:CYP27;
Organism Homo sapiens (Human)

PRO ID PR:Q02318
DAG View
PRO Name sterol 26-hydroxylase, mitochondrial (human)
Definition A cytochrome P450 27, mitochondrial that is encoded in the genome of human.
Short Label hCYP27A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q02318 (CYP27A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S280 Phosphorylation PhosphoSitePlus
S321 Phosphorylation HPRD   PhosphoSitePlus 20058876
K387 Methylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S280 F280 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
S321 I321 Biomuta DOID:5041 / esophageal cancer [ cosmic ]