iPTMnet Report for Q02241 (KIF23)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q02241 / KIF23_HUMAN
Protein Name Kinesin-like protein KIF23
Gene Name Name: KIF23
Synonyms:KNSL5,MKLP1;
Organism Homo sapiens (Human)

PRO ID PR:Q02241
DAG View
PRO Name kinesin-like protein KIF23 (human)
Definition A kinesin-like protein KIF23 that is encoded in the genome of human.
Short Label hKIF23
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q02241 (KIF23) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T8 Phosphorylation neXtProt   phospho.ELM 15282614
T13 Phosphorylation PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
S18 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
T20 Phosphorylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
Y29 Phosphorylation PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
Y111 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
S125 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
K149 Ubiquitination PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
S155 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 17081983
S160 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 16565220
K183 Acetylation PhosphoSitePlus
K188 Acetylation PhosphoSitePlus
S298 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
Y388 Phosphorylation PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
T450 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus 22067460, 18669648, 16964243, ...15282614
T493 Phosphorylation IEDB 35494241
K503 Ubiquitination PhosphoSitePlus
K517 Ubiquitination PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
K536 Ubiquitination PhosphoSitePlus
K543 Ubiquitination PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
K555 Ubiquitination PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
K571 Ubiquitination PhosphoSitePlus
K577 Ubiquitination PhosphoSitePlus
T580 Phosphorylation PhosphoSitePlus
Y582 Phosphorylation PhosphoSitePlus
K586 Sumoylation PhosphoSitePlus
K586 Ubiquitination PhosphoSitePlus
T595 Phosphorylation PhosphoSitePlus
K599 Ubiquitination PhosphoSitePlus
S605 Phosphorylation PhosphoSitePlus   UniProt 21406692
K624 Ubiquitination PhosphoSitePlus
K636 Ubiquitination PhosphoSitePlus
K643 Ubiquitination PhosphoSitePlus
K647 Sumoylation PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus
K655 Ubiquitination PhosphoSitePlus
K662 Sumoylation PhosphoSitePlus
S670 Phosphorylation PhosphoSitePlus
T679 Phosphorylation PhosphoSitePlus
S682 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983, 18220336, 16565220, ...22067460, 18669648
S684 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983, 18220336, 15302935, ...22067460, 18669648
S686 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460, 18669648, 18220336
S691 Phosphorylation PhosphoSitePlus
S714 Phosphorylation phospho.ELM   PhosphoSitePlus 15854913
S716 Phosphorylation Q9NRM7 (LATS2) , O95835 (LATS1) , Q15208 (STK38) phospho.ELM   PhosphoSitePlus   RLIMS-P 25786116, 22067460, 15854913, ...25658096
S718 Phosphorylation PhosphoSitePlus
S724 Phosphorylation PhosphoSitePlus
T735 Phosphorylation PhosphoSitePlus
Y736 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T738 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 23186163, ...16964243
K741 Ubiquitination PhosphoSitePlus
S744 Phosphorylation PhosphoSitePlus
K757 Ubiquitination PhosphoSitePlus
T758 O-Glycosylation GlyGen 30379171, 34019948
S812 Phosphorylation PhosphoSitePlus
S814 Phosphorylation Q9NRM7 (LATS2) , O95835 (LATS1) , Q15208 (STK38) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 25786116, 17081983, 25658096
T861 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S867 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 22067460, ...18669648, 20068231
T873 Phosphorylation PhosphoSitePlus
K877 Sumoylation PhosphoSitePlus
K877 Ubiquitination PhosphoSitePlus
Y881 Phosphorylation PhosphoSitePlus
T883 Phosphorylation PhosphoSitePlus
R884 Methylation PhosphoSitePlus
S889 Phosphorylation PhosphoSitePlus
T897 Phosphorylation PhosphoSitePlus
K899 Ubiquitination PhosphoSitePlus
S902 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 23186163, ...17081983
S906 Phosphorylation PhosphoSitePlus
S911 Phosphorylation Q96GD4 (AURKB) phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 18220336, 22945935, ...19203582, 16565220, 22067460, 18669648, 16461284
S912 Phosphorylation phospho.ELM   PRO   PhosphoSitePlus 18669648, 16565220, 18220336
T913 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
S924 Phosphorylation PhosphoSitePlus
T927 Phosphorylation PhosphoSitePlus   UniProt 23186163
S943 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
Y949 Phosphorylation PhosphoSitePlus
K956 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y29 Phosphorylation HPRD 15592455
S155 Phosphorylation HPRD 18669648, 17081983
S160 Phosphorylation HPRD 18669648, 16565220
T450 Phosphorylation HPRD 18669648, 20068231
S682 Phosphorylation HPRD 19007248, 20068231, 16565220
S684 Phosphorylation HPRD 15302935, 19007248, 16565220
Y736 Phosphorylation HPRD 18669648
T738 Phosphorylation HPRD 19413330, 18669648, 16964243
S812 Phosphorylation HPRD 20068231
S814 Phosphorylation HPRD 17081983, 20068231
S826 Phosphorylation HPRD 20068231
T861 Phosphorylation HPRD 18669648, 20068231
S867 Phosphorylation HPRD 17081983, 19007248, 18452278, ...19651622, 18669648, 20068231
T873 Phosphorylation HPRD 20068231
T897 Phosphorylation HPRD 20068231
S902 Phosphorylation HPRD 18669648, 17081983, 20068231
S911 Phosphorylation HPRD 18669648, 16565220, 19691289, ...20068231, 18452278
S912 Phosphorylation HPRD 18669648, 16565220, 20068231, ...18452278
T913 Phosphorylation HPRD 18669648, 17081983, 18452278
S934 Phosphorylation HPRD 19007248
Site PTM Type PTM Enzyme Score Source PMID
Y29 Phosphorylation HPRD 15592455
S155 Phosphorylation HPRD   phospho.ELM 18669648, 17081983
S160 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 16565220
T450 Phosphorylation HPRD   phospho.ELM 18669648, 20068231
Y582 Phosphorylation PhosphoSitePlus
T679 Phosphorylation HPRD 20068231
S682 Phosphorylation HPRD   PhosphoSitePlus 19007248, 16565220, 18669648, ...18452278, 20068231
S684 Phosphorylation HPRD   PhosphoSitePlus 18691976, 18491316, 15302935, ...19007248, 18452278, 18669648, 16565220, 20068231
S686 Phosphorylation HPRD   PhosphoSitePlus 17081983, 18452278, 18669648, ...20068231, 17924679
S708 Phosphorylation Q96GD4 (AURKB) HPRD   PhosphoSitePlus 20451386, 20068231
S710 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
S722 Phosphorylation HPRD 20068231
T757 Phosphorylation HPRD 18669648, 20068231
S763 Phosphorylation HPRD 17081983, 19007248, 18452278, ...19651622, 18669648, 20068231
T769 Phosphorylation HPRD 20068231
Y777 Phosphorylation PhosphoSitePlus
T793 Phosphorylation HPRD   PhosphoSitePlus 20068231
S798 Phosphorylation HPRD   PhosphoSitePlus 18669648, 17081983, 20068231
S802 Phosphorylation PhosphoSitePlus
S807 Phosphorylation HPRD   PhosphoSitePlus 19691289, 16565220, 18669648, ...18452278, 20068231
S808 Phosphorylation HPRD   PhosphoSitePlus 18669648, 16565220, 20068231, ...18452278
T809 Phosphorylation HPRD   PhosphoSitePlus 18669648, 17081983, 18452278
S820 Phosphorylation PhosphoSitePlus
T823 Phosphorylation PhosphoSitePlus
S830 Phosphorylation HPRD 19007248
Site PTM Type PTM Enzyme Score Source PMID
K48 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048111 (hKIF23/Phos:2) pS911,pS912 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T20 M20 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T56 A56 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K188 N188 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S298 F298 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T450 M450 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K523 N523 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y582 S582 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K662 E662 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S708 L708 Biomuta DOID:4159 / skin cancer [ cosmic ]
S710 F710 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S722 F722 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T735 M735 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S812 L812 Biomuta DOID:4159 / skin cancer [ cosmic ]
S814 F814 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S826 F826 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K877 N877 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]