iPTMnet Report for Q02153 (GUCY1B1)
Protein Information
| UniProt AC / UniProt ID | Q02153 / GCYB1_HUMAN |
| Protein Name | Guanylate cyclase soluble subunit beta-1 |
| Gene Name | Name: GUCY1B1 Synonyms:GUC1B3,GUCSB3,GUCY1B3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q02153 |
| PRO Name | guanylate cyclase soluble subunit beta-1 (human) |
| Definition | A guanylate cyclase soluble subunit beta-1 that is encoded in the genome of human. |
| Short Label | hGUCY1B1 |
| Category | organism-gene |
Q02153 (GUCY1B1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K165 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y192 | Phosphorylation | P12931 (SRC) | score2 | PhosphoSitePlus | 16079134 | |
| K471 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C497 | Methylation | score1 | IEDB | 31844290 | ||
| Y540 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K561 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y567 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K165 | N165 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| Y540 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View