Protein Information

Cytoscape View


UniProt AC / UniProt ID Q02040 / AK17A_HUMAN
Protein Name A-kinase anchor protein 17A
Gene Name Name: AKAP17A
Synonyms:CXYorf3,DXYS155E,SFRS17A,XE7;
Organism Homo sapiens (Human)

PRO ID PR:Q02040
DAG View
PRO Name A-kinase anchor protein 17A (human)
Definition An A-kinase anchor protein 17A that is encoded in the genome of human.
Short Label hAKAP17A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q02040 (AKAP17A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K44 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K118 Sumoylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
K317 Acetylation PhosphoSitePlus
K324 Acetylation PhosphoSitePlus
K339 Acetylation PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
S499 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
C522 Methylation IEDB 31844290
S537 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 24275569
S548 Phosphorylation PhosphoSitePlus
S574 O-Glycosylation GlyGen 30379171, 34019948
S584 Phosphorylation PhosphoSitePlus
R598 Methylation PhosphoSitePlus
S611 Phosphorylation PhosphoSitePlus
S633 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983
S638 Phosphorylation PhosphoSitePlus
T639 Phosphorylation PhosphoSitePlus
S640 Phosphorylation PhosphoSitePlus
S685 Phosphorylation PhosphoSitePlus
S687 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S444 Phosphorylation HPRD 20068231
S537 Phosphorylation HPRD 18212344, 19007248, 19691289, ...19651622, 18669648, 19415658, 20068231
S548 Phosphorylation HPRD 18452278
S633 Phosphorylation HPRD 19651622
S685 Phosphorylation HPRD 20068231
S687 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K86 N86 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S91 C91 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K350 N350 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S440 G440 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S548 F548 Biomuta DOID:4159 / skin cancer [ cosmic ]
S548 P548 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S633 T633 Biomuta DOID:4159 / skin cancer [ cosmic ]