iPTMnet Report for Q01995 (TAGLN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q01995 / TAGL_HUMAN
Protein Name Transgelin
Gene Name Name: TAGLN
Synonyms:SM22,WS3-10;
Organism Homo sapiens (Human)

PRO ID PR:Q01995
DAG View
PRO Name transgelin (human)
Definition A transgelin that is encoded in the genome of human.
Short Label hTAGLN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q01995 (TAGLN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K4 Acetylation PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
K17 Acetylation PhosphoSitePlus
Y22 Phosphorylation PhosphoSitePlus
C38 S-Nitrosylation dbSNO 25040305
S63 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
Y104 Phosphorylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
T109 Phosphorylation PhosphoSitePlus
T129 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
T139 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P 20068231, 25937534
Y145 Phosphorylation PhosphoSitePlus
K155 Acetylation PhosphoSitePlus
K160 Acetylation PhosphoSitePlus
T164 O-Glycosylation GlyGen 31373491
T164 Phosphorylation HPRD   PhosphoSitePlus 18212344
S166 O-Glycosylation GlyGen 34019948, 36580660, 31373491
S166 Phosphorylation PhosphoSitePlus   UniProt 21406692
S181 Phosphorylation Q05655 (PRKCD) , P17252 (PRKCA) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18212344, 11053353, 24275569, ...20166139, 22798525
R183 Methylation PhosphoSitePlus   UniProt 24129315
S186 O-Glycosylation GlyGen 31373491
S186 Phosphorylation PhosphoSitePlus
T191 O-Glycosylation GlyGen 34019948, 36580660, 31373491
T191 Phosphorylation PhosphoSitePlus
Y193 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107
R195 Methylation PhosphoSitePlus
R197 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K4 N4 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S68 I68 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K108 E108 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K108 N108 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T129 I129 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S135 C135 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S166 N166 Biomuta DOID:1319 / brain cancer [ cosmic ]
R195 Q195 Biomuta DOID:363 / uterine cancer [ icgc ]
R197 W197 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R197 Q197 Biomuta DOID:2531 / hematologic cancer [ cosmic ]