iPTMnet Report Q01986 Map2k1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q01986 / MP2K1_RAT
Protein Name	Dual specificity mitogen-activated protein kinase kinase 1
Gene Name	Name: Map2k1 Synonyms:Mek1,Prkmk1;
Organism	Rattus norvegicus (Rat)

PRO ID	PR:Q01986 DAG View
PRO Name	dual specificity mitogen-activated protein kinase kinase 1 (rat)
Definition	A dual specificity mitogen-activated protein kinase kinase 1 that is encoded in the genome of rat.
Short Label	rMAP2K1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q01986 (Map2k1) as Substrate

Q01986

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K104	Acetylation		score1	PhosphoSitePlus
	K192	Ubiquitination		score1	PhosphoSitePlus
	S212	Phosphorylation		score1	PhosphoSitePlus
	S218	Phosphorylation	F1M9C3 (Braf) , Q01986 (Map2k1)	score4	PhosphoSitePlus RLIMS-P	17314031, 8034665
	S222	Phosphorylation	Q01986 (Map2k1) , F1M9C3 (Braf)	score4	PhosphoSitePlus RLIMS-P	17314031, 8034665
	T286	Phosphorylation		score1	PhosphoSitePlus
	T292	Phosphorylation		score3	PhosphoSitePlus UniProt	14993270
	S298	Phosphorylation	Q64303 (Pak2) , Q62829 (Pak3) , P35465 (Pak1)	score4	PhosphoSitePlus UniProt	12876277, 17314031, 14993270
	K353	Acetylation		score1	PhosphoSitePlus
	T386	Phosphorylation		score1	PhosphoSitePlus

Q01986 (Map2k1) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	P04177 (Th)	S31	score2	PhosphoSitePlus	15471880
	P21708 (Mapk3)	T203	score3	PhosphoSitePlus	17314031, 15567062
	P21708 (Mapk3)	Y205	score3	PhosphoSitePlus	17314031, 15567062
	P49950 (Bcl2)	S70	score2	PhosphoSitePlus	15994315
	P63086 (Mapk1)	T183	score2	PhosphoSitePlus	17314031
	P63086 (Mapk1)	Y185	score2	PhosphoSitePlus	17314031
	Q01986 (Map2k1)	S218	score2	PhosphoSitePlus	17314031
	Q01986 (Map2k1)	S222	score2	PhosphoSitePlus	17314031