iPTMnet Report for Q01826 (SATB1)
Protein Information
| UniProt AC / UniProt ID | Q01826 / SATB1_HUMAN |
| Protein Name | DNA-binding protein SATB1 |
| Gene Name | Name: SATB1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q01826 |
| PRO Name | DNA-binding protein SATB1 (human) |
| Definition | A DNA-binding protein SATB1 that is encoded in the genome of human. |
| Short Label | hSATB1 |
| Category | organism-gene |
DAG ViewQ01826 (SATB1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K24 | Acetylation | score1 | PhosphoSitePlus | |||
| K29 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S38 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R42 | Methylation | score1 | PhosphoSitePlus | |||
| S47 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T48 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K51 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K65 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K136 | Acetylation | score3 | PhosphoSitePlus UniProt | 16630892 | ||
| K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S185 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 20694677, 16630892 | ||
| T188 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 20351170 | ||
| K194 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T298 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T310 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S313 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y331 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S341 | O-Glycosylation | score1 | GlyGen | 35132862, 29351928 | ||
| S341 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y346 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S354 | O-Glycosylation | score1 | GlyGen | 35132862, 29351928 | ||
| S366 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T466 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S469 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S512 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S524 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S557 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T630 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S633 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S637 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T649 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S652 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K735 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K744 | Sumoylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q01826 (SATB1) | T188 | O75925 (PIAS1) | unknown | eFIP | 20351170 | |
| Phosphorylation | Q01826 (SATB1) | S185 | Q13547 (HDAC1) | increased_association | eFIP | 20694677 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K24 | N24 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| K29 | Q29 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
| R42 | I42 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| R42 | K42 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K58 | N58 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K194 | T194 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S366 | L366 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ] | |
| S469 | R469 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T630 | M630 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S637 | P637 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T649 | R649 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S652 | L652 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
