iPTMnet Report for Q01780 (EXOSC10)
Protein Information
UniProt AC / UniProt ID | Q01780 / EXOSX_HUMAN |
Protein Name | Exosome complex component 10 |
Gene Name | Name: EXOSC10 Synonyms:PMSCL,PMSCL2,RRP6; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q01780 |
PRO Name | exosome component 10 (human) |
Definition | An exosome component 10 that is encoded in the genome of human. |
Short Label | hEXOSC10 |
Category | organism-gene |
Q01780 (EXOSC10) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
K37 | Acetylation | score1 | PhosphoSitePlus | |||
K48 | Ubiquitination | score1 | PhosphoSitePlus | |||
R79 | Methylation | score1 | PhosphoSitePlus | |||
Y90 | Phosphorylation | score1 | PhosphoSitePlus | |||
K109 | Acetylation | score1 | PhosphoSitePlus | |||
K136 | Ubiquitination | score1 | PhosphoSitePlus | |||
K150 | Ubiquitination | score1 | PhosphoSitePlus | |||
K168 | Sumoylation | score1 | PhosphoSitePlus | |||
K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
K186 | Ubiquitination | score1 | PhosphoSitePlus | |||
K190 | Ubiquitination | score1 | PhosphoSitePlus | |||
T196 | Phosphorylation | score1 | PhosphoSitePlus | |||
K201 | Sumoylation | score1 | PhosphoSitePlus | |||
K205 | Sumoylation | score1 | PhosphoSitePlus | |||
K210 | Ubiquitination | score1 | PhosphoSitePlus | |||
S217 | Phosphorylation | score1 | PhosphoSitePlus | |||
K218 | Ubiquitination | score1 | PhosphoSitePlus | |||
C288 | Methylation | score1 | IEDB | 31844290 | ||
S370 | Phosphorylation | score1 | PhosphoSitePlus | |||
K417 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y419 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y446 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y448 | Phosphorylation | score1 | PhosphoSitePlus | |||
K483 | Sumoylation | score1 | PhosphoSitePlus | |||
S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y491 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y530 | Phosphorylation | score1 | PhosphoSitePlus | |||
K583 | Sumoylation | score1 | PhosphoSitePlus | |||
K583 | Ubiquitination | score1 | PhosphoSitePlus | |||
K591 | Ubiquitination | score1 | PhosphoSitePlus | |||
K592 | Ubiquitination | score1 | PhosphoSitePlus | |||
S593 | Phosphorylation | score1 | PhosphoSitePlus | |||
K633 | Ubiquitination | score1 | PhosphoSitePlus | |||
S636 | Phosphorylation | score1 | PhosphoSitePlus | |||
K642 | Sumoylation | score1 | PhosphoSitePlus | |||
K671 | Ubiquitination | score1 | PhosphoSitePlus | |||
K679 | Ubiquitination | score1 | PhosphoSitePlus | |||
K680 | Ubiquitination | score1 | PhosphoSitePlus | |||
S698 | Phosphorylation | score1 | PhosphoSitePlus | |||
K710 | Sumoylation | score1 | PhosphoSitePlus | |||
K710 | Ubiquitination | score1 | PhosphoSitePlus | |||
K716 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y718 | Phosphorylation | score1 | PhosphoSitePlus | |||
K725 | Ubiquitination | score1 | PhosphoSitePlus | |||
T747 | Phosphorylation | score1 | PhosphoSitePlus | |||
K754 | Methylation | score1 | PhosphoSitePlus | |||
T784 | Phosphorylation | score1 | PhosphoSitePlus | |||
S785 | O-Glycosylation | score1 | GlyGen | 34725712, 33465208, 34019948, ... | ||
S785 | Phosphorylation | score1 | PhosphoSitePlus | |||
T790 | Phosphorylation | score1 | PhosphoSitePlus | |||
K813 | Ubiquitination | score1 | PhosphoSitePlus | |||
T816 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y818 | Phosphorylation | score1 | PhosphoSitePlus | |||
S821 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K826 | Sumoylation | score1 | PhosphoSitePlus | |||
K826 | Ubiquitination | score1 | PhosphoSitePlus | |||
K835 | Methylation | score1 | PhosphoSitePlus | |||
K835 | Sumoylation | score1 | PhosphoSitePlus | |||
T846 | Phosphorylation | score1 | PhosphoSitePlus | |||
S848 | Phosphorylation | score1 | PhosphoSitePlus | |||
K851 | Acetylation | score1 | PhosphoSitePlus | |||
K865 | Acetylation | score1 | PhosphoSitePlus | |||
S866 | Phosphorylation | score1 | PhosphoSitePlus | |||
S868 | Phosphorylation | score1 | PhosphoSitePlus | |||
T871 | Phosphorylation | score1 | PhosphoSitePlus | |||
K873 | Sumoylation | score1 | PhosphoSitePlus | |||
S874 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K136 | N136 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
K136 | * | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
K218 | E218 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S370 | P370 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y446 | H446 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y448 | C448 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K583 | E583 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
K592 | N592 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
S636 | G636 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
S785 | I785 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
T790 | A790 | Biomuta | DOID:2021 / placenta cancer [ cosmic ] | |
T816 | M816 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] |