iPTMnet Report for Q01668 (CACNA1D)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q01668 / CAC1D_HUMAN
Protein Name Voltage-dependent L-type calcium channel subunit alpha-1D
Gene Name Name: CACNA1D
Synonyms:CACH3,CACN4,CACNL1A2,CCHL1A2;
Organism Homo sapiens (Human)

PRO ID PR:Q01668
DAG View
PRO Name voltage-dependent L-type calcium channel subunit alpha-1D (human)
Definition A voltage-dependent L-type calcium channel subunit alpha-1D that is encoded in the genome of human.
Short Label hCACNA1D
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q01668 (CACNA1D) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S45 Phosphorylation PhosphoSitePlus
S81 Phosphorylation RLIMS-P 16973824
T476 Phosphorylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
C568 Methylation IEDB 31844290
S642 Phosphorylation PhosphoSitePlus
S849 Phosphorylation PhosphoSitePlus
S1490 Phosphorylation PhosphoSitePlus
S1540 Phosphorylation PhosphoSitePlus
T1549 Phosphorylation PhosphoSitePlus
S1700 Phosphorylation P17612 (PRKACA) neXtProt 19074150
S1773 Phosphorylation P17612 (PRKACA) neXtProt 19074150
T1809 Phosphorylation PhosphoSitePlus
Y1865 Phosphorylation PhosphoSitePlus
Y1867 Phosphorylation PhosphoSitePlus
S2123 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S507 Phosphorylation PhosphoSitePlus
S657 Phosphorylation HPRD 19651622
S662 Phosphorylation HPRD 19651622
S1925 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S507 F507 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
S657 N657 Biomuta DOID:4159 / skin cancer [ cosmic ]
S849 L849 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S2123 L2123 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]