iPTMnet Report for Q01650 (SLC7A5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q01650 / LAT1_HUMAN
Protein Name Large neutral amino acids transporter small subunit 1
Gene Name Name: SLC7A5
Synonyms:CD98LC,LAT1,MPE16;
Organism Homo sapiens (Human)

PRO ID PR:Q01650
DAG View
PRO Name large neutral amino acids transporter small subunit 1 (human)
Definition A large neutral amino acids transporter small subunit 1 that is encoded in the genome of human.
Short Label hSLC7A5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q01650 (SLC7A5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Ubiquitination PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
S31 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19369195, 21406692, 23186163, ...18691976, 19664994, 19651622, 18669648, 20068231
S35 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 19664994, 15302935, ...18452278, 19651622, 18669648, 20068231
T45 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
S225 Phosphorylation PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus
T507 Phosphorylation phospho.ELM   PhosphoSitePlus 16097034


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K19 N19 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K30 N30 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T507 A507 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]