iPTMnet Report for Q01546 (KRT76)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q01546 / K22O_HUMAN
Protein Name Keratin, type II cytoskeletal 2 oral
Gene Name Name: KRT76
Synonyms:KRT2B,KRT2P;
Organism Homo sapiens (Human)

PRO ID PR:Q01546
DAG View
PRO Name keratin, type II cytoskeletal 2 oral (human)
Definition A keratin, type II cytoskeletal 2 oral that is encoded in the genome of human.
Short Label hKRT76
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q01546 (KRT76) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
Y59 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
R85 Methylation PhosphoSitePlus
R110 Methylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
T189 Phosphorylation PhosphoSitePlus
K193 Acetylation PhosphoSitePlus
K193 Methylation PhosphoSitePlus
K193 Sumoylation PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
K200 Acetylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
Y361 Phosphorylation PhosphoSitePlus
Y376 Phosphorylation PhosphoSitePlus
T385 Phosphorylation PhosphoSitePlus
T427 Phosphorylation PhosphoSitePlus
K487 Acetylation PhosphoSitePlus
R495 Methylation PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
S544 Phosphorylation PhosphoSitePlus
Y549 Phosphorylation PhosphoSitePlus
S620 Phosphorylation HPRD 20068231
S626 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S18 F18 Biomuta DOID:1612 / breast cancer [ cosmic ]
S21 F21 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y59 * Biomuta DOID:263 / kidney cancer [ cosmic ]
R110 K110 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R110 S110 Biomuta DOID:1324 / lung cancer [ cosmic ]
K188 N188 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S196 F196 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S541 G541 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S626 A626 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S626 F626 Biomuta DOID:4159 / skin cancer [ cosmic ]