Protein Information

Cytoscape View


UniProt AC / UniProt ID Q01538 / MYT1_HUMAN
Protein Name Myelin transcription factor 1
Gene Name Name: MYT1
Synonyms:KIAA0835,KIAA1050,MTF1,MYTI,PLPB1;
Organism Homo sapiens (Human)

PRO ID PR:Q01538
DAG View
PRO Name myelin transcription factor 1 (human)
Definition A myelin transcription factor 1 that is encoded in the genome of human.
Short Label hMYT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q01538 (MYT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T36 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
S333 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
S406 Phosphorylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
S462 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
T606 Phosphorylation PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus
T609 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
Y619 Phosphorylation PhosphoSitePlus
T631 Phosphorylation PhosphoSitePlus
S989 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S429 Phosphorylation P53350 (PLK1) HPRD 12738781


Q01538 (MYT1) as PTM Enzyme



Substrate Site Score Source PMID
P06493-2 (CDK1) T14 HPRD 19413330, 18691976, 18452278, ...19651622, 9268380, 18669648, 9001210, 19901323, 19415658, 20068231, 20068230


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T36 I36 Biomuta DOID:363 / uterine cancer [ tcga ]
S245 G245 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S989 C989 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]