iPTMnet Report for Q01433 (AMPD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q01433 / AMPD2_HUMAN
Protein Name AMP deaminase 2
Gene Name Name: AMPD2
Organism Homo sapiens (Human)

PRO ID PR:Q01433
DAG View
PRO Name AMP deaminase 2 (human)
Definition An AMP deaminase 2 that is encoded in the genome of human.
Short Label hAMPD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q01433 (AMPD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation PhosphoSitePlus   UniProt 19690332
R33 Methylation PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
R45 Methylation PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K55 Ubiquitination PhosphoSitePlus
T63 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
K70 Ubiquitination PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus   UniProt 23186163
S84 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
Y91 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus   UniProt 18669648
S114 Phosphorylation PhosphoSitePlus   UniProt 20068231, 23186163, 17081983, ...24275569
K128 Ubiquitination PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
T134 Phosphorylation PhosphoSitePlus   UniProt 18669648
S136 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...24275569, 19690332, 20068231
S138 Phosphorylation IEDB   PhosphoSitePlus   UniProt 32387766, 23186163
Y143 Phosphorylation PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
Y200 Phosphorylation PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
T235 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
Y253 Phosphorylation PhosphoSitePlus
T260 Phosphorylation PhosphoSitePlus
K318 Sumoylation PhosphoSitePlus
K360 Ubiquitination PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
K439 Ubiquitination PhosphoSitePlus
Y440 Phosphorylation PhosphoSitePlus
S446 Phosphorylation PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
T455 Phosphorylation PhosphoSitePlus
K462 Acetylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
K479 Ubiquitination PhosphoSitePlus
Y667 Phosphorylation PhosphoSitePlus
K758 Ubiquitination PhosphoSitePlus
R785 Methylation PhosphoSitePlus
S821 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
R6 Methylation PhosphoSitePlus
R18 Methylation PhosphoSitePlus
S19 Phosphorylation HPRD 18669648, 18212344, 20068231
S37 Phosphorylation HPRD 18669648, 17081983
S70 Phosphorylation HPRD 18669648
S87 Phosphorylation HPRD   PhosphoSitePlus 17081983, 18767875, 18077418, ...18669648, 20068231, 18212344
T107 Phosphorylation HPRD 20166139, 18669648
S109 Phosphorylation HPRD 19651622, 20166139, 18669648, ...18088087, 20068231
S111 Phosphorylation HPRD 20166139
Y116 Phosphorylation PhosphoSitePlus
S177 Phosphorylation HPRD 20068231
S794 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R6 W6 Biomuta DOID:9256 / colorectal cancer [ icgc ]