iPTMnet Report for Q01432 (AMPD3)
Protein Information
| UniProt AC / UniProt ID | Q01432 / AMPD3_HUMAN |
| Protein Name | AMP deaminase 3 |
| Gene Name | Name: AMPD3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q01432 |
| PRO Name | AMP deaminase 3 (human) |
| Definition | An AMP deaminase 3 that is encoded in the genome of human. |
| Short Label | hAMPD3 |
| Category | organism-gene |
Q01432 (AMPD3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K7 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K23 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K27 | Methylation | score1 | PhosphoSitePlus | |||
| K27 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K35 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K61 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S83 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S85 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S87 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S103 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S107 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
| K157 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y170 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S178 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K298 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K348 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K388 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K407 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K422 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S431 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K432 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y433 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y435 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T521 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S525 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S530 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S538 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S615 | Phosphorylation | score1 | IEDB | 35494241 | ||
| K711 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K721 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K731 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T732 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S83 | Phosphorylation | score0 | HPRD | 20058876 | ||
| S85 | Phosphorylation | score0 | HPRD | 20058876 | ||
| S87 | Phosphorylation | score0 | HPRD | 20058876 | ||
| Y170 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K67 | E67 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S87 | Y87 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S94 | Y94 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S96 | Y96 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K157 | R157 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| S178 | Y178 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S178 | F178 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K348 | R348 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| K711 | N711 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K731 | N731 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View