iPTMnet Report for Q01320 (Top2a)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q01320 / TOP2A_MOUSE
Protein Name DNA topoisomerase 2-alpha
Gene Name Name: Top2a
Synonyms:Top-2,Top2;
Organism Mus musculus (Mouse)

PRO ID PR:Q01320
DAG View
PRO Name DNA topoisomerase 2-alpha (mouse)
Definition A DNA topoisomerase 2-alpha that is encoded in the genome of mouse.
Short Label mTOP2A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q01320 (Top2a) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
S28 Phosphorylation phospho.ELM   PhosphoSitePlus 19144319
K155 Ubiquitination PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus
Y327 Phosphorylation PhosphoSitePlus
C391 S-Nitrosylation dbSNO 20925432
S394 Phosphorylation PhosphoSitePlus
C404 S-Nitrosylation dbSNO 20925432
S448 Phosphorylation PhosphoSitePlus
T601 Phosphorylation PhosphoSitePlus
K610 Acetylation PhosphoSitePlus
K621 Acetylation PhosphoSitePlus
K621 Ubiquitination PhosphoSitePlus
K797 Ubiquitination PhosphoSitePlus
C996 S-Nitrosylation dbSNO 20925432
S1105 Phosphorylation PhosphoSitePlus
S1211 Phosphorylation PhosphoSitePlus   UniProt 21183079
S1239 Phosphorylation PhosphoSitePlus
T1245 Phosphorylation PhosphoSitePlus   UniProt 21183079
S1255 Phosphorylation PhosphoSitePlus
S1291 Phosphorylation PhosphoSitePlus
S1293 Phosphorylation PhosphoSitePlus
S1295 Phosphorylation PhosphoSitePlus
S1298 Phosphorylation PhosphoSitePlus
S1299 Phosphorylation PhosphoSitePlus
S1302 Phosphorylation PhosphoSitePlus
T1323 Phosphorylation PhosphoSitePlus   UniProt 21183079
S1328 Phosphorylation PhosphoSitePlus   UniProt 21183079
S1333 Phosphorylation PhosphoSitePlus   UniProt 21183079
T1350 Phosphorylation PhosphoSitePlus   UniProt 21183079
T1367 Phosphorylation PhosphoSitePlus
S1370 Phosphorylation PhosphoSitePlus
S1371 Phosphorylation PhosphoSitePlus
S1373 Phosphorylation PhosphoSitePlus   UniProt 21183079
S1379 Phosphorylation PhosphoSitePlus
S1384 Phosphorylation PhosphoSitePlus
S1388 Phosphorylation PhosphoSitePlus   UniProt 21183079
K1418 Acetylation UniProt 23806337
S1419 Phosphorylation PhosphoSitePlus
S1421 Phosphorylation PhosphoSitePlus
S1422 Phosphorylation PhosphoSitePlus
K1438 Acetylation UniProt 23806337
S1439 Phosphorylation PhosphoSitePlus
S1441 Phosphorylation PhosphoSitePlus
S1448 Phosphorylation PhosphoSitePlus
S1465 Phosphorylation PhosphoSitePlus
S1466 Phosphorylation PhosphoSitePlus
S1467 Phosphorylation PhosphoSitePlus
S1469 Phosphorylation PhosphoSitePlus
S1470 Phosphorylation PhosphoSitePlus
S1472 Phosphorylation PhosphoSitePlus
T1501 Phosphorylation PhosphoSitePlus
S1521 Phosphorylation PhosphoSitePlus   UniProt 21183079