Protein Information

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UniProt AC / UniProt ID Q01196 / RUNX1_HUMAN
Protein Name Runt-related transcription factor 1
Gene Name Name: RUNX1
Synonyms:AML1,CBFA2;
Organism Homo sapiens (Human)

PRO ID PR:Q01196
DAG View
PRO Name runt-related transcription factor 1 (human)
Definition A runt-related transcription factor 1 that is encoded in the genome of human.
Short Label hRUNX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q01196 (RUNX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T14 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 15302935, ...19690332
S17 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T18 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S21 Phosphorylation Q00534 (CDK6) , P06493 (CDK1) phospho.ELM   PhosphoSitePlus   Signor   UniProt 15302935, 18669648, 23186163, ...21059642
K24 Acetylation PhosphoSitePlus   UniProt 19608861
K24 Ubiquitination PhosphoSitePlus
K43 Acetylation PhosphoSitePlus   UniProt 19608861
K43 Ubiquitination PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K188 Acetylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus   UniProt 23186163
S199 Phosphorylation PhosphoSitePlus
R206 Methylation PhosphoSitePlus
T207 Phosphorylation PhosphoSitePlus
R210 Methylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
T219 Phosphorylation PhosphoSitePlus
R223 Methylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
S229 Phosphorylation phospho.ELM 18669648
T230 Phosphorylation phospho.ELM 18669648
S238 Phosphorylation PhosphoSitePlus
S249 Phosphorylation P28482 (MAPK1) , Q00534 (CDK6) , Q9H2X6 (HIPK2) , P24941 (CDK2) , P06493 (CDK1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 30349386, 18695000, 25405766, ...16046550, 16917507, 8668214, 19690332
S253 Phosphorylation PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
Y258 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
S266 Phosphorylation P28482 (MAPK1) , P24941 (CDK2) , Q00534 (CDK6) , P06493 (CDK1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 30349386, 25405766, 16046550, ...8668214, 19690332
S268 Phosphorylation PhosphoSitePlus   UniProt 19690332
T273 Phosphorylation P24941 (CDK2) , Q9H2X6 (HIPK2) , P06493 (CDK1) , P28482 (MAPK1) , Q00534 (CDK6) PhosphoSitePlus   RLIMS-P   Signor   UniProt 16046550, 18695000, 25405766
S276 Phosphorylation P24941 (CDK2) , P28482 (MAPK1) , P06493 (CDK1) , Q00534 (CDK6) , Q9H2X6 (HIPK2) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18695000, 25405766, 21059642, ...17015473, 16046550, 16917507, 19690332
S292 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
T296 Phosphorylation PhosphoSitePlus   UniProt 23186163
R319 Methylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
T331 Phosphorylation PhosphoSitePlus
S397 Phosphorylation P06493 (CDK1) , Q00534 (CDK6) PhosphoSitePlus   Signor 21059642
S423 Phosphorylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y453 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T14 Phosphorylation HPRD 19651622, 18669648, 15302935, ...20068231
S17 Phosphorylation HPRD 19651622, 18669648, 20068231
T18 Phosphorylation HPRD 19651622, 18669648
S21 Phosphorylation HPRD 19651622, 18669648, 15302935, ...20068231
K24 Acetylation PR:000007102 (EP300) PRO 14752096
K43 Acetylation PR:000007102 (EP300) PRO 14752096
S229 Phosphorylation HPRD 18669648
T230 Phosphorylation HPRD 18669648
S249 Phosphorylation Q9H2X6 (HIPK2) HPRD 169175071
S276 Phosphorylation Q9H2X6 (HIPK2) HPRD 16917507
T284 Phosphorylation HPRD 20068231
T285 Phosphorylation HPRD 20068231
S291 Phosphorylation HPRD 20068231
S292 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T458 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T41 Phosphorylation HPRD 19651622, 18669648, 15302935, ...20068231
S44 Phosphorylation HPRD 19651622, 18669648, 20068231
T45 Phosphorylation HPRD 19651622, 18669648
S48 Phosphorylation HPRD   PhosphoSitePlus 19651622, 18669648, 15302935, ...20068231
S256 Phosphorylation HPRD 18669648
T257 Phosphorylation HPRD 18669648
S276 Phosphorylation Q00534 (CDK6) , P06493 (CDK1) , P24941 (CDK2) , P28482 (MAPK1) , P27361 (MAPK3) neXtProt   PhosphoSitePlus 17015473, 15475366
S293 Phosphorylation P06493 (CDK1) , Q00534 (CDK6) , P28482 (MAPK1) , P24941 (CDK2) , P27361 (MAPK3) neXtProt   PhosphoSitePlus 17015473, 15475366
T300 Phosphorylation P28482 (MAPK1) , P24941 (CDK2) , Q00534 (CDK6) , P06493 (CDK1) , P27361 (MAPK3) neXtProt   PhosphoSitePlus 17015473, 15475366
S303 Phosphorylation P06493 (CDK1) , Q00534 (CDK6) , P24941 (CDK2) , P28482 (MAPK1) , P27361 (MAPK3) neXtProt   PhosphoSitePlus 17015473, 17023045, 15475366
T311 Phosphorylation HPRD 20068231
T312 Phosphorylation HPRD 20068231
S318 Phosphorylation HPRD 20068231
S319 Phosphorylation HPRD 20068231
T323 Phosphorylation PhosphoSitePlus
S424 Phosphorylation P06493 (CDK1) PhosphoSitePlus 21059642
S462 Phosphorylation P27361 (MAPK3) , P28482 (MAPK1) PhosphoSitePlus 15475366


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000028561 (hRUNX1/Ac:1) acK24,acK43 PR:000007102 (EP300) PRO 14752096