Protein Information

Cytoscape View


UniProt AC / UniProt ID Q01085 / TIAR_HUMAN
Protein Name Nucleolysin TIAR
Gene Name Name: TIAL1
Organism Homo sapiens (Human)

PRO ID PR:Q01085
DAG View
PRO Name nucleolysin TIAR (human)
Definition A nucleolysin TIAR that is encoded in the genome of human.
Short Label hTIAL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q01085 (TIAL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y50 Phosphorylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
T85 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
K122 Acetylation PhosphoSitePlus   UniProt 19608861
K122 Ubiquitination PhosphoSitePlus
K130 Methylation PhosphoSitePlus
Y140 Phosphorylation PhosphoSitePlus
Y146 Phosphorylation PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus   UniProt 20068231
K203 Ubiquitination PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
T282 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T10 Phosphorylation HPRD 20068231
Y50 Phosphorylation HPRD 15592455
S105 Phosphorylation HPRD 20068231
S115 Phosphorylation HPRD 18452278
S201 Phosphorylation HPRD 18691976, 20068231
Site PTM Type PTM Enzyme Score Source PMID
T10 Phosphorylation HPRD 20068231
S52 Phosphorylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
Y67 Phosphorylation HPRD   PhosphoSitePlus 15592455
S122 Phosphorylation HPRD 20068231
S132 Phosphorylation HPRD 18452278
S218 Phosphorylation HPRD 18691976, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S226 T226 Biomuta DOID:363 / uterine cancer [ tcga ]