iPTMnet Report for Q01085 (TIAL1)
Protein Information
| UniProt AC / UniProt ID | Q01085 / TIAR_HUMAN |
| Protein Name | Nucleolysin TIAR |
| Gene Name | Name: TIAL1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q01085 |
| PRO Name | nucleolysin TIAR (human) |
| Definition | A nucleolysin TIAR that is encoded in the genome of human. |
| Short Label | hTIAL1 |
| Category | organism-gene |
Q01085 (TIAL1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y50 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C51 | Methylation | score1 | IEDB | 31844290 | ||
| K76 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S88 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K90 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S115 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K122 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K122 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K130 | Methylation | score1 | PhosphoSitePlus | |||
| T134 | O-Glycosylation | score1 | GlyGen | 30379171, 33214551, 22121020, ... | ||
| S137 | O-Glycosylation | score1 | GlyGen | 30379171, 33214551, 22121020, ... | ||
| Y140 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y146 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S201 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
| K203 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S226 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S278 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T282 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T10 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y50 | Phosphorylation | score0 | HPRD | 15592455 | ||
| S105 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S115 | Phosphorylation | score0 | HPRD | 18452278 | ||
| S201 | Phosphorylation | score0 | HPRD | 18691976, 20068231 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T10 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S52 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S53 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S57 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y67 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 15592455 | ||
| S122 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S132 | Phosphorylation | score0 | HPRD | 18452278 | ||
| S218 | Phosphorylation | score0 | HPRD | 18691976, 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y146 | C146 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S226 | T226 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
DAG View