iPTMnet Report for Q01064 (PDE1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q01064 / PDE1B_HUMAN
Protein Name Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
Gene Name Name: PDE1B
Synonyms:PDES1B;
Organism Homo sapiens (Human)

PRO ID PR:Q01064
DAG View
PRO Name dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (human)
Definition A dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B that is encoded in the genome of human.
Short Label hPDE1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q01064 (PDE1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C17 S-Nitrosylation dbSNO 26338901
Y41 Phosphorylation PhosphoSitePlus
Y62 Phosphorylation PhosphoSitePlus
Y71 Phosphorylation PhosphoSitePlus
T144 Phosphorylation PhosphoSitePlus
T152 Phosphorylation PhosphoSitePlus
T201 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
T375 Phosphorylation PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S466 Phosphorylation HPRD 15345747


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y71 H71 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T201 A201 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T201 P201 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S372 N372 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]