iPTMnet Report for Q00975 (CACNA1B)
Protein Information
UniProt AC / UniProt ID | Q00975 / CAC1B_HUMAN |
Protein Name | Voltage-dependent N-type calcium channel subunit alpha-1B |
Gene Name | Name: CACNA1B Synonyms:CACH5,CACNL1A5; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q00975 |
PRO Name | voltage-dependent N-type calcium channel subunit alpha-1B (human) |
Definition | A voltage-dependent N-type calcium channel subunit alpha-1B that is encoded in the genome of human. |
Short Label | hCACNA1B |
Category | organism-gene |
Q00975 (CACNA1B) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S208 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y245 | Phosphorylation | score1 | PhosphoSitePlus | |||
N256 | N-Glycosylation | score3 | GlyGen UniProt | 34234349 | ||
K374 | Ubiquitination | score1 | PhosphoSitePlus | |||
S411 | Phosphorylation | P28482 (MAPK1) , P27361 (MAPK3) | score2 | neXtProt | 16406008 | |
T421 | Phosphorylation | score1 | PhosphoSitePlus | |||
S446 | Phosphorylation | P27361 (MAPK3) , P28482 (MAPK1) | score2 | neXtProt | 16406008 | |
S455 | Phosphorylation | score1 | phospho.ELM | 17081983 | ||
S761 | Phosphorylation | score1 | PhosphoSitePlus | |||
S766 | Phosphorylation | score1 | PhosphoSitePlus | |||
S971 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1242 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1248 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1331 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1445 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1447 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1450 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1869 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1870 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1941 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1944 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1960 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1968 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2001 | Phosphorylation | score1 | PhosphoSitePlus | |||
T2009 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2023 | Phosphorylation | score1 | PhosphoSitePlus | |||
T2024 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2119 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2120 | Phosphorylation | Q9UQM7 (CAMK2A) | score1 | Signor | 16982421 | |
Y2128 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2129 | Phosphorylation | P17612 (PRKACA) | score3 | neXtProt PhosphoSitePlus | 16982421 | |
S2233 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2256 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y2259 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2266 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N256 | S256 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S446 | F446 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T1941 | N1941 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S1960 | Y1960 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S1968 | * | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
T2024 | S2024 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T2024 | M2024 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] | |
S2129 | T2129 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
S2256 | Y2256 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |