iPTMnet Report for Q00975 (CACNA1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q00975 / CAC1B_HUMAN
Protein Name Voltage-dependent N-type calcium channel subunit alpha-1B
Gene Name Name: CACNA1B
Synonyms:CACH5,CACNL1A5;
Organism Homo sapiens (Human)

PRO ID PR:Q00975
DAG View
PRO Name voltage-dependent N-type calcium channel subunit alpha-1B (human)
Definition A voltage-dependent N-type calcium channel subunit alpha-1B that is encoded in the genome of human.
Short Label hCACNA1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q00975 (CACNA1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S208 Phosphorylation PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
S411 Phosphorylation P28482 (MAPK1) , P27361 (MAPK3) neXtProt 16406008
T421 Phosphorylation PhosphoSitePlus
S446 Phosphorylation P27361 (MAPK3) , P28482 (MAPK1) neXtProt 16406008
S455 Phosphorylation phospho.ELM 17081983
S761 Phosphorylation PhosphoSitePlus
S766 Phosphorylation PhosphoSitePlus
S971 Phosphorylation PhosphoSitePlus
K1242 Ubiquitination PhosphoSitePlus
K1248 Ubiquitination PhosphoSitePlus
K1331 Ubiquitination PhosphoSitePlus
S1445 Phosphorylation PhosphoSitePlus
K1447 Ubiquitination PhosphoSitePlus
T1450 Phosphorylation PhosphoSitePlus
T1869 Phosphorylation PhosphoSitePlus
T1870 Phosphorylation PhosphoSitePlus
T1941 Phosphorylation PhosphoSitePlus
T1944 Phosphorylation PhosphoSitePlus
S1960 Phosphorylation PhosphoSitePlus
S1968 Phosphorylation PhosphoSitePlus
S2001 Phosphorylation PhosphoSitePlus
T2009 Phosphorylation PhosphoSitePlus
S2023 Phosphorylation PhosphoSitePlus
T2024 Phosphorylation PhosphoSitePlus
S2119 Phosphorylation PhosphoSitePlus
S2120 Phosphorylation Q9UQM7 (CAMK2A) Signor 16982421
Y2128 Phosphorylation PhosphoSitePlus
S2129 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus 16982421
S2233 Phosphorylation PhosphoSitePlus
S2256 Phosphorylation PhosphoSitePlus
Y2259 Phosphorylation PhosphoSitePlus
S2266 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S455 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S446 F446 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S455 I455 Biomuta DOID:3571 / liver cancer [ icgc ]
T1941 N1941 Biomuta DOID:363 / uterine cancer [ tcga ]
S1960 Y1960 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S1968 * Biomuta DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]
T2024 S2024 Biomuta DOID:1324 / lung cancer [ cosmic ]
T2024 M2024 Biomuta DOID:1793 / pancreatic cancer [ tcga ] DOID:10534 / stomach cancer [ cosmic, icgc ]
Y2128 * Biomuta DOID:3571 / liver cancer [ icgc ]