iPTMnet Report for Q00796 (SORD)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q00796 / DHSO_HUMAN
Protein Name Sorbitol dehydrogenase
Gene Name Name: SORD
Organism Homo sapiens (Human)

PRO ID PR:Q00796
DAG View
PRO Name sorbitol dehydrogenase (human)
Definition A sorbitol dehydrogenase that is encoded in the genome of human.
Short Label hSORD
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q00796 (SORD) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 25944712
K6 Acetylation PhosphoSitePlus
K6 Ubiquitination PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
Y25 Phosphorylation PhosphoSitePlus
Y51 Phosphorylation PhosphoSitePlus
Y54 Phosphorylation PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
T122 Phosphorylation PhosphoSitePlus
K134 Acetylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
C140 Methylation IEDB 31844290
R167 Methylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
T208 Phosphorylation PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus   UniProt 24275569
S225 Phosphorylation PhosphoSitePlus   UniProt 24275569
K226 Ubiquitination PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K339 Acetylation PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T203 Phosphorylation HPRD 20068231
S206 Phosphorylation HPRD 20068231
T208 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 Y11 Biomuta DOID:4159 / skin cancer [ cosmic ]
T122 M122 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R167 T167 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]