Protein Information

Cytoscape View


UniProt AC / UniProt ID Q00688 / FKBP3_HUMAN
Protein Name Peptidyl-prolyl cis-trans isomerase FKBP3
Gene Name Name: FKBP3
Synonyms:FKBP25;
Organism Homo sapiens (Human)

PRO ID PR:Q00688
DAG View
PRO Name peptidyl-prolyl cis-trans isomerase FKBP3 (human)
Definition A peptidyl-prolyl cis-trans isomerase FKBP3 that is encoded in the genome of human.
Short Label hFKBP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q00688 (FKBP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 25944712
T11 Phosphorylation PhosphoSitePlus
R16 Methylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
S36 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P   UniProt 29361176, 17081983, 20068231
K42 Ubiquitination PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
K73 Acetylation PhosphoSitePlus
T75 Phosphorylation PhosphoSitePlus
S77 Phosphorylation HPRD   PhosphoSitePlus 20068231
S79 Phosphorylation HPRD 20068231
K80 Ubiquitination PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
T98 Phosphorylation PhosphoSitePlus   RLIMS-P 29361176
S100 Phosphorylation PhosphoSitePlus   RLIMS-P 29361176
T103 Phosphorylation RLIMS-P 29361176
K110 Acetylation PhosphoSitePlus
T147 Phosphorylation HPRD 20068231
S152 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
K154 Acetylation PhosphoSitePlus
K160 Acetylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K170 Acetylation PhosphoSitePlus   UniProt 19608861
K170 Ubiquitination PhosphoSitePlus
R173 Methylation PhosphoSitePlus
T181 Phosphorylation HPRD   PhosphoSitePlus 20068231
S183 Phosphorylation HPRD   PhosphoSitePlus 20068231
K187 Methylation PhosphoSitePlus
Y198 Phosphorylation HPRD   PhosphoSitePlus 20068231
K200 Acetylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ]
K27 E27 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S36 W36 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K86 Q86 Biomuta DOID:363 / uterine cancer [ tcga ]
K86 N86 Biomuta DOID:1324 / lung cancer [ cosmic ]
T147 A147 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
T147 I147 Biomuta DOID:363 / uterine cancer [ tcga ]
K160 R160 Biomuta DOID:9256 / colorectal cancer [ tcga ]